Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its associated
symptoms, named coronavirus disease 2019 (COVID-19), have rapidly spread worldwide …

Aging, hypertension, diabetes, hypoxia/obstructive sleep apnea (OSA), obesity, vitamin
B12/folate deficiency, depression, and traumatic brain injury synergistically promote diverse …

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study
(https://abcdstudy. org/) is to establish a national longitudinal cohort of 9 and 10 year olds …

Adolescence is a developmental period when physical and cognitive abilities are optimized,
when social skills are consolidated, and when sexuality, adolescent behaviors, and frontal …

Background Cigarette smoking has been linked with both increased and decreased risk for
Alzheimer's disease (AD). This is relevant for the US military because the prevalence of …

Alcohol use disorder (AUD) has been associated with neurodegenerative diseases such as
Alzheimer's and Parkinson's disease. Prolonged excessive alcohol intake contributes to …

Toll-like receptors play an important role in the innate immune response, although emerging
evidence indicates their role in brain injury and neurodegeneration. Alcohol abuse induces …

Alcohol and substance abuse disorders involve continued use of substances despite
negative consequences, ie loss of behavioral control of drug use. The frontal-cortical areas …

The Neurobiology of Adolescent Drinking in Adulthood (NADIA) Consortium has focused on
the impact of adolescent binge drinking on brain development, particularly on effects that …

Background Toll-like receptor (TLR) signaling is emerging as an important component of
neurodegeneration. TLR7 senses viral RNA and certain endogenous miRNAs to initiate …