Coffee is one of the most popular beverages consumed worldwide. Roasted coffee is a
complex mixture of thousands of bioactive compounds, and some of them have numerous …

Neurological and psychiatric disorders are a category of chronic diseases that are
widespread and pose serious mental and physical health problems for patients. The …

Many complex traits or diseases, such as infectious and autoimmune diseases, cancer,
xenobiotics exposure, neurodevelopmental and neurodegenerative diseases, as well as the …

Coffee is one of the most popular and consumed beverages worldwide, and caffeine is its
best-known component, present also in many other beverages (tea, soft drinks, energy …

Depression is a global public health issue with high morbidity and mortality, which tends to
cause fatigue, inability to concentrate, insomnia, and loss of appetite, especially represented …

Coffee is one of the most widely consumed beverages worldwide, and epidemiology studies
associate higher coffee consumption with decreased rates of mortality and decreased rates …

Sex is an important factor that contributes to the clinical and biological heterogeneities in
Alzheimer's disease (AD), but the regulatory mechanisms underlying sex disparity in AD are …

Alzheimer's disease (AD) is the most prevalent kind of dementia with roughly 135 million
cases expected in the world by 2050. Unfortunately, current medications for the treatment of …

Schizophrenia is a disease with a complex etiology that significantly impairs the functioning
of patients. In recent years, there has been increasing focus on the importance of the gut …

Background Recent studies have reported an association between dietary caffeine intake
(coffee and tea) and the presence of depressive symptoms. However, the findings are not …