The incidence of inflammatory bowel diseases (IBD) emerged with Westernisation of dietary
habits worldwide. Crohn's disease and ulcerative colitis are chronic debilitating conditions …

S100A8 and S100A9 (also known as MRP8 and MRP14, respectively) are Ca2+ binding
proteins belonging to the S100 family. They often exist in the form of heterodimer, while …

The S100 protein family consists of 24 members functionally distributed into three main
subgroups: those that only exert intracellular regulatory effects, those with intracellular and …

The S100 family proteins possess a variety of intracellular and extracellular functions. They
interact with multiple receptors and signal transducers to regulate pathways that govern …

Atherosclerosis is an arterial disease associated with dyslipidemia, abnormal arterial
calcification and oxidative stress. It has been shown that a continued chronic inflammatory …

Sepsis, the foremost contributor to mortality in intensive care unit patients, arises from an
uncontrolled systemic response to invading infections, resulting in extensive harm across …

Calprotectin (CLP) is a heterodimer formed by two S-100 calcium-binding cytosolic proteins,
S100A8 and S100A9. It is a multifunctional protein expressed mainly by neutrophils and …

Elevated neutrophil count is associated with higher risk of major adverse cardiac events
including myocardial infarction and early development of heart failure. Neutrophils …

S100 proteins are small proteins that are only expressed in vertebrates. They are widely
expressed in many different cell types and are involved in the regulation of calcium …

Asthma is a generalized term that describes a scope of distinct pathologic phenotypes of
variable severity, which share a common complication of reversible airflow obstruction …