Malaria parasite plasmepsins: More than just plain old degradative pepsins
AS Nasamu, AJ Polino, ES Istvan… - Journal of Biological …, 2020 - ASBMB
Plasmepsins are a group of diverse aspartic proteases in the malaria parasite Plasmodium.
Their functions are strikingly multifaceted, ranging from hemoglobin degradation to secretory …
Their functions are strikingly multifaceted, ranging from hemoglobin degradation to secretory …
Iron dysregulation in COVID‐19 and reciprocal evolution of SARS‐CoV‐2: Natura nihil frustra facit
Y Gupta, D Maciorowski, B Medernach… - Journal of cellular …, 2022 - Wiley Online Library
After more than a year of the COVID‐19 pandemic, SARS‐CoV‐2 infection rates with newer
variants continue to devastate much of the world. Global healthcare systems are …
variants continue to devastate much of the world. Global healthcare systems are …
Plasmodium falciparum Proteases as new drug targets with special focus on Metalloproteases
PJ Mahanta, K Lhouvum - Molecular and Biochemical Parasitology, 2024 - Elsevier
Malaria poses a significant global health threat particularly due to the prevalence of
Plasmodium falciparum infection. With the emergence of parasite resistance to existing …
Plasmodium falciparum infection. With the emergence of parasite resistance to existing …
Understanding the structural basis of substrate recognition by Plasmodium falciparum plasmepsin V to aid in the design of potent inhibitors
Plasmodium falciparum plasmepsin V (PfPMV) is an essential aspartic protease required for
parasite survival, thus, considered as a potential drug target. This study reports the first …
parasite survival, thus, considered as a potential drug target. This study reports the first …
Biochemical characterization of plasmepsin V from Plasmodium vivax Thailand isolates: substrate specificity and enzyme inhibition
K Sappakhaw, R Takasila, P Sittikul… - Molecular and …, 2015 - Elsevier
Plasmepsin V (PMV) is a Plasmodium aspartic protease responsible for the cleavage of the
Plasmodium export element (PEXEL) motif, which is an essential step for export of PEXEL …
Plasmodium export element (PEXEL) motif, which is an essential step for export of PEXEL …
India's computational biology growth and challenges
C Chakraborty, S Bandyopadhyay… - Interdisciplinary Sciences …, 2016 - Springer
India's computational science is growing swiftly due to the outburst of internet and
information technology services. The bioinformatics sector of India has been transforming …
information technology services. The bioinformatics sector of India has been transforming …
[PDF][PDF] Iron dysregulation in COVID‐19 and reciprocal evolution of SARS‐CoV‐2: Natura nihil frustra facit
B Medernach, DP Becker, R Durvasula, CR Libertin… - researchgate.net
After more than a year of the COVID‐19 pandemic, SARS‐CoV‐2 infection rates with newer
variants continue to devastate much of the world. Global healthcare systems are …
variants continue to devastate much of the world. Global healthcare systems are …