Clinical status of efflux resistance mechanisms in gram-negative bacteria

A Davin-Regli, JM Pages, A Ferrand - Antibiotics, 2021 - mdpi.com
Antibiotic efflux is a mechanism that is well-documented in the phenotype of multidrug
resistance in bacteria. Efflux is considered as an early facilitating mechanism in the bacterial …

Large-scale genomic analysis of global Klebsiella pneumoniae plasmids reveals multiple simultaneous clusters of carbapenem-resistant hypervirulent strains

A Spadar, J Perdigão, S Campino, TG Clark - Genome medicine, 2023 - Springer
Abstract Background Klebsiella pneumoniae (Kp) Gram-negative bacteria cause
nosocomial infections and rapidly acquire antimicrobial resistance (AMR), which makes it a …

Species identification and antibiotic resistance prediction by analysis of whole-genome sequence data by use of ARESdb: an analysis of isolates from the Unyvero …

I Ferreira, S Beisken, L Lueftinger… - Journal of clinical …, 2020 - Am Soc Microbiol
Whole-genome sequencing (WGS) is now routinely performed in clinical microbiology
laboratories to assess isolate relatedness. With appropriately developed analytics, the same …

Genomic Epidemiology of Carbapenem-Resistant Klebsiella in Qatar: Emergence and Dissemination of Hypervirulent Klebsiella pneumoniae Sequence Type 383 …

CKM Tsui, F Ben Abid, K Al Ismail… - Antimicrobial agents …, 2023 - Am Soc Microbiol
The emergence of carbapenem-resistant, hypervirulent Klebsiella pneumoniae is a new
threat to health care. We studied the molecular epidemiology of carbapenem-resistant …

Genomics of Klebsiella pneumoniae Species Complex Reveals the Circulation of High-Risk Multidrug-Resistant Pandemic Clones in Human, Animal, and …

S Morgado, E Fonseca, AC Vicente - Microorganisms, 2022 - mdpi.com
The Klebsiella species present a remarkable genetic and ecological diversity, being
ubiquitous in nature. In particular, the Klebsiella pneumoniae species complex (KpSC) has …

Genomic network analysis of environmental and livestock F-type plasmid populations

W Matlock, KK Chau, M AbuOun… - The ISME …, 2021 - academic.oup.com
F-type plasmids are diverse and of great clinical significance, often carrying genes
conferring antimicrobial resistance (AMR) such as extended-spectrum β-lactamases …

Population genomics uncovers global distribution, antimicrobial resistance, and virulence genes of the opportunistic pathogen Klebsiella aerogenes

Y Feng, Y Yang, Y Hu, Y Xiao, Y Xie, L Wei, H Wen… - Cell Reports, 2024 - cell.com
Klebsiella aerogenes is an understudied and clinically important pathogen. We therefore
investigate its population structure by genome analysis aligned with metadata. We …

Oral colonisation by antimicrobial-resistant Gram-negative bacteria among long-term care facility residents: prevalence, risk factors, and molecular epidemiology

MNT Le, S Kayama, M Yoshikawa, T Hara… - … Resistance & Infection …, 2020 - Springer
Background For residents of long-term care facilities (LTCFs), antimicrobial-resistant
bacteria (ARB) are a risk factor, yet their oral colonisation, potentially leading to aspiration …

In-depth analysis of Klebsiella aerogenes resistome, virulome and plasmidome worldwide

S Morgado, É Fonseca, F Freitas, R Caldart… - Scientific Reports, 2024 - nature.com
Klebsiella aerogenes is an emergent pathogen associated with outbreaks of carbapenem-
resistant strains. To date, studies focusing on K. aerogenes have been small-scale and/or …

[HTML][HTML] Phylogenetic analysis and population structure of Pseudomonas alloputida

H Passarelli-Araujo, SH Jacobs, GR Franco… - Genomics, 2021 - Elsevier
The Pseudomonas putida group comprises strains with biotechnological and clinical
relevance. P. alloputida was proposed as a new species and highlighted the …