The subject of crystal engineering started in the 1970s with the study of topochemical
reactions in the solid state. A broad chemical definition of crystal engineering was published …

The ΔpKa rule is commonly applied by chemists and crystal engineers as a guideline for the
rational design of molecular salts and co-crystals. For multi-component crystals containing …

Pharmaceutical cocrystals represent a distinctive class of crystal engineered
multicomponent systems consisting an API and a crystal former non-covalently linked …

Intermolecular interactions of organic, inorganic, and organometallic compounds are the key
to many composition–structure and structure–property networks. In this review, some of …

The ability to rationally design and predictably construct crystalline solids has been the
hallmark of crystal engineering research. To date, numerous examples of multicomponent …

Room temperature phosphorescence (RTP) with long afterglow from molecular crystals has
been the subject of growing interest for researchers over the last decade due to its potential …

X-ray photoelectron spectroscopy (XPS) has emerged as a technique that allows for
characterization and classification of hydrogen bonding and proton transfer interactions in …

Achieving the desired solubility and dissolution of active pharmaceutical ingredients (APIs)
continues to be a big challenge in the pharmaceutical industry. In this regard …

It is important to be able to identify the precise position of H-atoms in hydrogen bonding
interactions to fully understand the effects on the structure and properties of organic crystals …

Green solvents have been used to varying degrees in processes such as extraction,
separation, synthesis, catalysis, analysis, materials preparation and so on; meanwhile more …