Pesticides, environment, and food safety

FP Carvalho - Food and energy security, 2017 - Wiley Online Library
Agrochemicals have enabled to more than duplicate food production during the last century,
and the current need to increase food production to feed a rapid growing human population …

Pesticides: an update of human exposure and toxicity

S Mostafalou, M Abdollahi - Archives of toxicology, 2017 - Springer
Pesticides are a family of compounds which have brought many benefits to mankind in the
agricultural, industrial, and health areas, but their toxicities in both humans and animals …

LRRK2 and idiopathic Parkinson's disease

EM Rocha, MT Keeney, R Di Maio… - Trends in …, 2022 - cell.com
The etiology of idiopathic Parkinson's disease (iPD) is multifactorial, and both genetics and
environmental exposures are risk factors. While mutations in leucine-rich repeat kinase-2 …

The bowel and beyond: the enteric nervous system in neurological disorders

M Rao, MD Gershon - Nature reviews Gastroenterology & hepatology, 2016 - nature.com
The enteric nervous system (ENS) is large, complex and uniquely able to orchestrate
gastrointestinal behaviour independently of the central nervous system (CNS). An intact …

Preventing Parkinson's disease: an environmental agenda

BR De Miranda, SM Goldman… - Journal of …, 2022 - content.iospress.com
Fueled by aging populations and continued environmental contamination, the global burden
of Parkinson's disease (PD) is increasing. The disease, or more appropriately diseases …

The vermiform appendix impacts the risk of developing Parkinson's disease

BA Killinger, Z Madaj, JW Sikora, N Rey… - Science translational …, 2018 - science.org
The pathogenesis of Parkinson's disease (PD) involves the accumulation of aggregated α-
synuclein, which has been suggested to begin in the gastrointestinal tract. Here, we …

Pathogenesis of Parkinson disease—the gut–brain axis and environmental factors

L Klingelhoefer, H Reichmann - Nature Reviews Neurology, 2015 - nature.com
Parkinson disease (PD) follows a defined clinical pattern, and a range of nonmotor
symptoms precede the motor phase. The predominant early nonmotor manifestations are …

Pesticides and human chronic diseases: evidences, mechanisms, and perspectives

S Mostafalou, M Abdollahi - Toxicology and applied pharmacology, 2013 - Elsevier
Along with the wide use of pesticides in the world, the concerns over their health impacts are
rapidly growing. There is a huge body of evidence on the relation between exposure to …

Epidemiology and etiology of Parkinson's disease: a review of the evidence

K Wirdefeldt, HO Adami, P Cole, D Trichopoulos… - European journal of …, 2011 - Springer
The etiology of Parkinson's disease (PD) is not well understood but likely to involve both
genetic and environmental factors. Incidence and prevalence estimates vary to a large …

Application, monitoring and adverse effects in pesticide use: The importance of reinforcement of Good Agricultural Practices (GAPs)

WH Leong, SY Teh, MM Hossain, T Nadarajaw… - Journal of environmental …, 2020 - Elsevier
This review intends to integrate the relevant information that is related to pesticide
applications in food commodities and will cover three main sections. The first section …