Regulation of microRNA biogenesis and its crosstalk with other cellular pathways

T Treiber, N Treiber, G Meister - Nature reviews Molecular cell biology, 2019 - nature.com
MicroRNAs (miRNAs) are short non-coding RNAs that inhibit the expression of target genes
by directly binding to their mRNAs. miRNAs are transcribed as precursor molecules, which …

Browsing the oldest antioxidant enzyme: catalase and its multiple regulation in cancer

M Galasso, S Gambino, MG Romanelli… - Free Radical Biology …, 2021 - Elsevier
Aerobic organisms possess numerous antioxidant enzymatic families, including catalases,
superoxide dismutases (SODs), peroxiredoxins (PRDXs), and glutathione peroxidases …

Exosomes provide a protective and enriched source of miRNA for biomarker profiling compared to intracellular and cell-free blood

L Cheng, RA Sharples, BJ Scicluna… - Journal of extracellular …, 2014 - Taylor & Francis
Introduction microRNA (miRNA) are small non-coding RNA species that are transcriptionally
processed in the host cell and released extracellularly into the bloodstream. Normally …

PI3k/AKT signaling pathway: Erythropoiesis and beyond

M Jafari, E Ghadami, T Dadkhah… - Journal of cellular …, 2019 - Wiley Online Library
Erythropoiesis is a multi‐step process that involves the differentiation of hematopoietic stem
cells into mature red blood cells (RBCs). This process is regulated by several signaling …

Pervasive roles of microRNAs in cardiovascular biology

EM Small, EN Olson - Nature, 2011 - nature.com
First recognized as regulators of development in worms and fruitflies, microRNAs are
emerging as pivotal modulators of mammalian cardiovascular development and disease …

MicroRNAs and their role on fish oxidative stress during xenobiotic environmental exposures

MA Burgos-Aceves, A Cohen, Y Smith… - … and Environmental safety, 2018 - Elsevier
There is a growing global concern about the health implications of xenobiotics, which have
harmful effects to both humans and wildlife. Among them, teleost fish are known as very …

The roles of microRNAs in mouse development

B DeVeale, J Swindlehurst-Chan… - Nature Reviews Genetics, 2021 - nature.com
Hundreds of microRNAs (miRNAs) are expressed in distinct spatial and temporal patterns
during embryonic and postnatal mouse development. The loss of all miRNAs through the …

The role of miRNAs in regulating gene expression networks

AM Gurtan, PA Sharp - Journal of molecular biology, 2013 - Elsevier
MicroRNAs (miRNAs) are key regulators of gene expression. They are conserved across
species, expressed across cell types, and active against a large proportion of the …

From stem cell to red cell: regulation of erythropoiesis at multiple levels by multiple proteins, RNAs, and chromatin modifications

SM Hattangadi, P Wong, L Zhang… - Blood, The Journal …, 2011 - ashpublications.org
This article reviews the regulation of production of RBCs at several levels. We focus on the
regulated expansion of burst-forming unit-erythroid erythroid progenitors by glucocorticoids …

Alternative miRNA biogenesis pathways and the interpretation of core miRNA pathway mutants

JS Yang, EC Lai - Molecular cell, 2011 - cell.com
Since the establishment of a canonical animal microRNA biogenesis pathway driven by the
RNase III enzymes Drosha and Dicer, an unexpected variety of alternative mechanisms that …