Advances in copper complexes as anticancer agents

C Santini, M Pellei, V Gandin, M Porchia… - Chemical …, 2014 - ACS Publications
Medicinal inorganic chemistry offers additional opportunities for the design of therapeutic
agents not accessible to organic compounds. 1− 3 The wide range of coordination numbers …

Noble metals in medicine: Latest advances

S Medici, M Peana, VM Nurchi, JI Lachowicz… - Coordination Chemistry …, 2015 - Elsevier
History shows that metal-based drugs and remedies have been known and used since very
ancient times. For example, silver was employed in the treatment of wounds and ulcers …

Isosteric Replacement of Sulfur to Selenium in a Thiosemicarbazone: Promotion of Zn (II) Complex Dissociation and Transmetalation to Augment Anticancer Efficacy

B Kaya, M Gholam Azad, M Suleymanoglu… - Journal of Medicinal …, 2024 - ACS Publications
We implemented isosteric replacement of sulfur to selenium in a novel thiosemicarbazone
(PPTP4c4mT) to create a selenosemicarbazone (PPTP4c4mSe) that demonstrates …

Synthesis, characterization, and photophysical properties of heteroleptic copper (I) complexes with functionalized 3-(2′-pyridyl)-1, 2, 4-triazole chelating ligands

JL Chen, XF Cao, JY Wang, LH He, ZY Liu… - Inorganic …, 2013 - ACS Publications
A new series of mononuclear copper (I) complexes (1–9) with functionalized 3-(2′-pyridyl)-
1, 2, 4-triazole chelating ligands, as well as the halide and/or phosphine ancillary ligands …

Binuclear Schiff base copper (II) complexes: Syntheses, crystal structures, HSA interaction and anti-cancer properties

S Jiang, H Ni, F Liu, S Gu, P Yu, Y Gou - Inorganica Chimica Acta, 2020 - Elsevier
Three binuclear Schiff base copper (II) complexes:[Cu 2 (HL1) 2 (CH 3 OH)(NO 3)]· NO 3
(1),[Cu 2 (HL2) 2 (CH 3 OH) 2]· 2NO 3 (2), and [Cu 2 (HL3) 2 (C 2 H 5 OH) 2]· 2NO 3 …

Synthesis, structure characterization and biological activity of selected metal complexes of sulfonamide Schiff base as a primary ligand and some mixed ligand …

CM Sharaby, MF Amine, AA Hamed - Journal of Molecular Structure, 2017 - Elsevier
The current work reports synthesis of metal complexes and mixed ligand complexes of a
novel sulfonamide Schiff base ligand (HL) resulted from the condensation of sulfametrole …

Copper (II) complexes with isoxazole Schiff bases: Synthesis, spectroscopic investigation, DNA binding and nuclease activities, antioxidant and antimicrobial studies

N Ganji, A Rambabu, N Vamsikrishna… - Journal of Molecular …, 2018 - Elsevier
Three novel Cu (II) complexes 1 [Cu (L 1) 2], 2 [Cu (L 2) 2] and 3 [Cu (L 3) 2], where L 1 H= 2-
((3, 4-dimethylisoxazol-5-ylimino) methyl)-6-tert-butylphenol, L 2 H= 2-((3, 4 …

The anti-breast cancer stem cell potency of copper (i)-non-steroidal anti-inflammatory drug complexes

A Johnson, X Feng, K Singh, F Ortu, K Suntharalingam - Molecules, 2023 - mdpi.com
Cancer stem cells (CSCs) are thought to be partly responsible for metastasis and cancer
relapse. Currently, there are no effective therapeutic options that can remove CSCs at …

Short-Bite PNP Ligand-Supported Rare Tetranuclear [Cu4I4] Clusters: Structural and Photoluminescence Studies

S Naik, JT Mague, MS Balakrishna - Inorganic Chemistry, 2014 - ACS Publications
The group 11 metal complexes of two short-bite PNP ligands, C6H5N {P (OC6H3 (OMe-
o)(C3H5-p)) 2} 2 (1) and C6H5N {P (OC6H4C3H5-o) 2} 2 (2), are described. Ligands 1 and …

Dithiocarbazate based oxidomethoxidovanadium (V) and mixed-ligand oxidovanadium (IV) complexes: Study of solution behavior, DNA binding, and anticancer …

G Sahu, SA Patra, M Mohanty, S Lima… - Journal of Inorganic …, 2022 - Elsevier
In this work, one oxidomethoxidovanadium (V)[VVO (L)(OMe)](1) and two mixed-ligand
oxidovanadium (IV)[V IV O (L)(phen)](2), and [V IV O (L)(bipy)](3) complexes have been …