Combinatorial liquid-phase synthesis of structurally diverse benzimidazole libraries

CM Yeh, CL Tung, CM Sun - Journal of combinatorial chemistry, 2000 - ACS Publications
An expedient liquid-phase synthesis for construction of the diverse benzimidazole libraries
is described. Nucleophilic aryl substitution of poly (ethylene glycol)-supported 4-fluoro-3 …

Solid phase Diels–Alder/retro Diels–Alder reactions. A new method for traceless linker strategy

L Blanco, R Bloch, E Bugnet, S Deloisy - Tetrahedron Letters, 2000 - Elsevier
A resin-bound furan has been efficiently synthesized from Merrifield resin. This new polymer
reacts with an acetylenic dienophile to afford a thermally stable Diels–Alder adduct …

1, 3-Dipolar cycloaddition of nitrile oxides to (R)-1-(1-phenylethyl)-3-[(E)-arylmethylidene] tetrahydro-4 (1H)-pyridinones: synthesis of enantiomerically pure spiro …

RS Kumar, S Perumal, HB Kagan, R Guillot - Tetrahedron: Asymmetry, 2007 - Elsevier
The 1, 3-dipolar cycloaddition of (R)-1-(1-phenylethyl)-3-[(E)-arylmethylidene] tetrahydro-4
(1H)-pyridinones to nitrile oxides proceeds chemo-, regio-, and stereoselectively affording …

Intermolecular conjugate addition of alkyl radicals on solid phase

X Zhu, A Ganesan - Journal of Combinatorial Chemistry, 1999 - ACS Publications
The conjugate addition of alkyl radicals, generated photolytically from the corresponding
Barton esters, to acrylate immobilized on solid-phase was investigated. Using cross-linked …

Solid-phase synthesis of 2-substituted-3-(substituted sulfanyl)-1, 2, 4-benzothiadiazine 1, 1-dioxide library

S Makino, T Okuzumi, E Nakanishi, T Tsuji - Tetrahedron letters, 2002 - Elsevier
The first solid-phase synthesis of 2-substituted-3-(substituted sulfanyl)-1, 2, 4-
benzothiadiazine 1, 1-dioxides has been developed. Synthesis of the title compounds was …

Development of a 9-borabicyclo [3.3. 1] nonane-mediated solid-phase Suzuki coupling for the preparation of dihydrostilbene analogs

RD Ferguson, N Su, RA Smith - Tetrahedron letters, 2003 - Elsevier
A novel 9-borabicyclo [3.3. 1] nonane-mediated solid-phase Suzuki coupling was developed
to generate dihydrostilbenes (bibenzyls) and related compounds. Using optimized …

Combinatorial synthesis of PEG oligomer libraries

JA Riggs-Sauthier, NN Ekwuribe - US Patent 8,329,958, 2012 - Google Patents
(57) ABSTRACT A simple chain-extending approach Was established for the scale-up of the
monoprotected monodisperse PEG diol mate rials. Reactions of THP-(OCH2CH2) n4OMs …

Facile characterization of polymer-supported reagents using cross polarization magic angle spinning method in solid state 13C-NMR

K Shikii, H Seki, K Yamaguchi, W Disadee… - Chemical and …, 2004 - jstage.jst.go.jp
In general, CP method is not adapted to the absolute quantitation because the efficiency of
cross polarization might be different depends on the compounds. When the target peak …

A new conception of polymeric supports for the solid phase peptide synthesis: rigidity and porosity as determinant factors for the success in industrial applications

S Cantone - 2008 - openstarts.units.it
In questo studio di tesi sono stati sviluppati ed ottimizzati nuovi supporti rigidi per la sintesi in
fase solida in collaborazione con l'azienda Resindion srl.(Mitsubishi Chemical Corporation) …

[PDF][PDF] Combinatorial Applications of N-acyliminium Ion Intermediates in the Synthesis of Homoallylic Amines

WJN Meester - 2002 - dare.uva.nl
Inn the preceding chapters, it was shown that N-acyliminium ion chemistry can be efficientlyy
carried out on a solid phase, provided that an appropriate linker system is used. Withh the …