Antiviral effect of phytochemicals from medicinal plants: Applications and drug delivery strategies

S Ben-Shabat, L Yarmolinsky, D Porat… - Drug delivery and …, 2020 - Springer
Viral infections affect three to five million patients annually. While commonly used antivirals
often show limited efficacy and serious adverse effects, herbal extracts have been in use for …

A review on pharmacological activities and synergistic effect of quercetin with small molecule agents

H Zou, H Ye, R Kamaraj, T Zhang, J Zhang, P Pavek - Phytomedicine, 2021 - Elsevier
Background Quercetin is a natural flavonoid, which widely exists in nature, such as tea,
coffee, apples, and onions. Numerous studies have showed that quercetin has multiple …

Potential of dietary polyphenols for protection from age-related decline and neurodegeneration: a role for gut microbiota?

FC Ross, DE Mayer, J Horn, JF Cryan… - Nutritional …, 2024 - Taylor & Francis
Many epidemiological studies have shown the beneficial effects of a largely plant-based
diet, and the strong association between the consumption of a Mediterranean-type diet with …

Quercetin-and rutin-based nano-formulations for cancer treatment: A systematic review of improved efficacy and molecular mechanisms

M Ghanbari-Movahed, A Mondal, MH Farzaei… - Phytomedicine, 2022 - Elsevier
Background Natural products, with incredible chemical diversity, have been widely studied
for their antitumor potential. Quercetin (QU) and quercetin glycoside (rutin), both …

Physical stability and antioxidant activity of citrus flavonoids in arabic gum-stabilized microcapsules: Modulation of whey protein concentrate

Y Hu, Y Li, W Zhang, G Kou, Z Zhou - Food Hydrocolloids, 2018 - Elsevier
In this study, gum arabic (GA)-stabilized emulsions and microcapsules were utilized to
encapsulate the flavonoids extracted from citrus peels. Microcapsules were produced by …

Plant protein-based hydrophobic fine and ultrafine carrier particles in drug delivery systems

H Malekzad, H Mirshekari… - Critical reviews in …, 2018 - Taylor & Francis
For thousands of years, plants and their products have been used as the mainstay of
medicinal therapy. In recent years, besides attempts to isolate the active ingredients of …

Citrus Flavonoids: Biological Activities, Implementation in Skin Health, and Topical Applications: A Review

Z Sebghatollahi, M Ghanadian, P Agarwal… - ACS Food Science & …, 2022 - ACS Publications
Citrus fruits are one of the most popular sources of dietary flavonoids, such as hesperidin,
hesperetin, naringin, naringenin, quercetin, rutin, diosmin, diosmetin, kaempferol, myricetin …

Nanoemulsion improves the neuroprotective effects of curcumin in an experimental model of Parkinson's disease

OV Ramires Júnior, BS Alves, PAB Barros… - Neurotoxicity …, 2021 - Springer
Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor
dysfunction. Recent studies have shown that curcumin (CUR) has neuroprotective effects in …

Application of nanomaterials in the treatment of intracerebral hemorrhage

X Zhang, S Khan, R Wei, Y Zhang… - Journal of Tissue …, 2023 - journals.sagepub.com
Intracerebral hemorrhage (ICH) is a non-traumatic hemorrhage caused by the rupture of
blood vessels in the brain parenchyma, with an acute mortality rate of 30%‒40%. Currently …

Formulation and characterization of quercetin-loaded oil in water nanoemulsion and evaluation of hypocholesterolemic activity in rats

HY Son, MS Lee, E Chang, SY Kim, B Kang, H Ko… - Nutrients, 2019 - mdpi.com
Due to poor water solubility and high susceptibility to chemical degradation, the applications
of quercetin have been limited. This study investigated the effects of pH on the formation of …