[HTML][HTML] 1, 3, 4-Thiadiazoles of pharmacological interest: Recent trends in their synthesis via tandem 1, 3-dipolar cycloaddition

AS Shawali - Journal of advanced research, 2014 - Elsevier
This review article presents a survey of the utility of a new synthetic strategy for 1, 3, 4-
thiadiazole derivatives based on reactions of nitrilimines with various functionalized sulfur …

Synthesis, characterization, and pharmacological evaluation of some novel thiadiazoles and thiazoles incorporating pyrazole moiety as anticancer agents

SM Gomha, TA Salah, AO Abdelhamid - Monatshefte für Chemie …, 2015 - Springer
Abstract Two series of novel 2-[[1-(5-methyl-1-phenyl-5-substituted-1 H-pyrazol-4-yl)
ethylidene] hydrazono]-3-phenyl-2, 3-dihydro-1, 3, 4-thiadiazole derivatives and 2-[5-(4 …

[PDF][PDF] Synthesis of 1, 3, 4-thiadiazole derivatives and microbiological activities: A review

GAD Barbosa, AP de Aguiar - Rev. Virtual Quim, 2019 - s3.sa-east-1.amazonaws.com
Bacterial resistance associated to different antibiotics is a limitation for the treatment of
infections and this has stimulated the development of new antimicrobial agents. In this …

Chitosan-strontium oxide nanocomposite: preparation, characterization, and catalytic potency in thiadiazoles synthesis

KD Khalil, SM Riyadh, NS Alkayal, AH Bashal… - Polymers, 2022 - mdpi.com
Recently, Strontium oxide (SrO) nanoparticles (NPs) and hybrids outperformed older
commercial catalysts in terms of catalytic performance. Herein, we present a microwave …

Synthesis and evaluation of new 1, 3, 4-thiadiazole derivatives as potent antifungal agents

AÇ Karaburun, U Acar Çevik, D Osmaniye, BN Sağlık… - Molecules, 2018 - mdpi.com
With the goal of obtaining a novel bioactive compound with significant antifungal activity, a
series of 1, 3, 4-thiadiazole derivatives (3a–3l) were synthesized and characterized. Due to …

A novel series of thiosemicarbazone drugs: from synthesis to structure

HP Ebrahimi, JS Hadi, TA Alsalim, TS Ghali… - … Acta Part A: Molecular …, 2015 - Elsevier
A new series of thiosemicarbazones (TSCs) and their 1, 3, 4-thiadiazolines (TDZs)
containing acetamide group have been synthesized from thiosemicarbazide compounds by …

[PDF][PDF] Design and synthesis of thiadiazole derivatives as antidiabetic agents

PA Datar, TA Deokule - Med. Chem, 2014 - pdfs.semanticscholar.org
Thiadiazole compounds have versatile activities such as anti-microbial, anti-inflammatory,
anticancer, etc. Present study involves design of thiadiazole compounds as antidiabetic …

Design, synthesis and anticancer activity of novel pyrimidine and pyrimidine-thiadiazole hybrid glycosides

HS Khalaf, HEM Tolan, MAA Radwan… - … nucleotides & nucleic …, 2020 - Taylor & Francis
Abstract New 1, 3, 4-thiadiazole thioglycosides linked to substituted pyrimidines were
synthesized via glycosylation of 1, 3, 4-thiadiazole thiol compounds. Also, novel 1, 2, 3 …

Synthetic and biological aspects of thiadiazoles and their condensed derivatives: an overview

J Dwivedi, N Kaur, D Kishore, S Kumari… - Current Topics in …, 2016 - ingentaconnect.com
The three heteroatoms containing five membered heterocycles such as thiadiazoles have
been extensively studied due to their important pharmacological activities. The thiadiazole …

Design of New Thiadiazole Derivatives with Improved Antidiabetic Activity

CND Dou, GS Dembele, MGR Kone… - Journal of …, 2023 - univ-pau.hal.science
Diabetes is a serious, long-term (or chronic) disease that occurs when a person's blood
sugar levels are high because their body cannot produce enough insulin, or does not …