Dopamine is a small and relatively simple molecule that fulfills diverse functions. Within the
brain, it acts as a classical neurotransmitter whose attenuation or overactivity can result in …

The classical biogenic amine neurotransmitters—dopamine, noradrenaline, and 5-
hydroxytryptamine—control a variety of functions including locomotion, autonomic function …

Disruption of the mouse dopamine transporter gene results in spontaneous hyperlocomotion
despite major adaptive changes, such as decreases in neurotransmitter and receptor levels …

Selective blockers of the norepinephrine transporter (NET) inhibit dopamine uptake in the
prefrontal cortex. This suggests that dopamine in this region is normally cleared by the …

Palacı́n, Manuel, Raúl Estévez, Joan Bertran, and Antonio Zorzano. Molecular Biology of
Mammalian Plasma Membrane Amino Acid Transporters. Physiol. Rev. 78: 969–1054, 1998 …

Methamphetamine is a drug that is significantly abused worldwide. Although long–lasting
depletion of dopamine and other dopamine nerve terminal markers has been reported in …

Among the neuromodulators that regulate prefrontal cortical circuit function, the
catecholamine transmitters norepinephrine (NE) and dopamine (DA) stand out as powerful …

Parkinson's disease is a complex neurodegenerative disorder characterized by the death of
brain dopamine neurons. In mammals, dopamine neuronal degeneration can be triggered …

Background The plasma membrane neurotransmitter transporters terminate
neurotransmissions by the reuptake of the released neurotransmitters. The transporters for …

Noradrenaline, also known as norepinephrine, has a wide range of activities and effects on
most brain cell types. Its reuptake from the synaptic cleft heavily relies on the noradrenaline …