Bioorthogonal chemistry enables researchers to manipulate bioactive molecules in living
systems. These highly selective and biocompatible reactions can be carried out in various …

The advent of the click chemistry paradigm has profoundly transformed the design of
functional polymeric materials. Among the various reactions in the click chemistry toolkit, the …

The design of cell-instructive biomaterials for tissue engineering and regenerative medicine
is at a crossroads. Although the conventional tissue engineering approach is top-down (cells …

Recreating functional tissues through bioengineering strategies requires steering of
complex cell fate decisions. Notch, a juxtacrine signaling pathway, regulates cell fate and …

Blood vessels grow and remodel in response to mechanical stimuli. Many computational
models capture this process phenomenologically, by assuming stress homeostasis, but this …

Surface modification of materials with proteins has various biological applications, and
hence the methodology for surface modification needs to accommodate a wide range of …

Cardiovascular tissue engineering (CVTE) aims to create living tissues, with the ability to
grow and remodel, as replacements for diseased blood vessels and heart valves. Despite …

Rebuilding the kidney in the context of tissue engineering offers a major challenge as the
organ is structurally complex and has a high variety of specific functions. Recreation of …

In Notch signaling, the Jagged1-Notch3 ligand-receptor pairing is implicated for regulating
the phenotype maturity of vascular smooth muscle cells. However, less is known about the …

A polymer microarray based on the supramolecular ureido‐pyrimidinone (UPy) moiety is
fabricated to screen antimicrobial materials for their ability to support cell adhesion. UPy …