Inflammation is the body's first line of defense against infection or injury, responding to
challenges by activating innate and adaptive responses. Microbes have evolved a diverse …

Francisella tularensis is a facultative intracellular gram-negative pathogen and the
etiological agent of the zoonotic disease tularemia. Recent advances in the field of …

Francisella tularensis causes the human disease tularemia. F. tularensis is able to survive
and replicate within macrophages, a trait that has been correlated with its high virulence, but …

Francisella spp. are highly infectious and virulent bacteria that cause the zoonotic disease
tularemia. Knowledge is lacking for the virulence factors expressed by Francisella and how …

Francisella tularensis causes systemic disease in humans and other mammals, with high
morbidity and mortality associated with inhalation-acquired infection. F. tularensis is a …

Francisella tularensis is a Gram-negative intracellular pathogen and the causative agent of
the disease tularemia. Inhalation of as few as 10 bacteria is sufficient to cause severe …

Francisella tularensis is a highly virulent gram-negative intracellular bacterium that causes
the zoonotic disease tularemia. Essential for its virulence is the ability to multiply within host …

The intracellular Gram-negative bacterium Francisella tularensis causes the disease
tularemia and is known for its ability to subvert host immune responses. Previous work from …

Studies of immune responses to Francisella have been conducted for well over 50 years.
Here, the basic parameters of innate and adaptive immune responses to Francisella are …

Background Bacillus anthracis, Francisella tularensis, and Yersinia pestis are bacterial
pathogens that can cause anthrax, lethal acute pneumonic disease, and bubonic plague …