American Society of Hematology 2021 guidelines for management of venous thromboembolism: prevention and treatment in patients with cancer

GH Lyman, M Carrier, C Ay, M Di Nisio… - Blood …, 2021 - ashpublications.org
Background: Venous thromboembolism (VTE) is a common complication among patients
with cancer. Patients with cancer and VTE are at a markedly increased risk for morbidity and …

[HTML][HTML] Biomedical applications of engineered heparin-based materials

EN Zare, D Khorsandi, A Zarepour, H Yilmaz… - Bioactive Materials, 2024 - Elsevier
Heparin is a negatively charged polysaccharide with various chain lengths and a hydrophilic
backbone. Due to its fascinating chemical and physical properties, nontoxicity …

CONSORT Harms 2022 statement, explanation, and elaboration: updated guideline for the reporting of harms in randomised trials

DR Junqueira, L Zorzela, S Golder, Y Loke, JJ Gagnier… - Bmj, 2023 - bmj.com
Randomised controlled trials remain the reference standard for healthcare research on
effects of interventions, and the need to report both benefits and harms is essential. The …

Surviving sepsis campaign: international guidelines for management of sepsis and septic shock: 2016

A Rhodes, LE Evans, W Alhazzani, MM Levy… - Intensive care …, 2017 - Springer
Objective To provide an update to “Surviving Sepsis Campaign Guidelines for Management
of Sepsis and Septic Shock: 2012”. Design A consensus committee of 55 international …

Heparin-induced thrombocytopenia (HIT): Review of incidence, diagnosis, and management

M Hogan, JS Berger - Vascular Medicine, 2020 - journals.sagepub.com
Heparin-induced thrombocytopenia (HIT) is a life and limb-threatening complication of
heparin exposure. Here, we review the pathogenesis, incidence, diagnosis, and …

Heparin-mimicking polymers: synthesis and biological applications

SJ Paluck, TH Nguyen, HD Maynard - Biomacromolecules, 2016 - ACS Publications
Heparin is a naturally occurring, highly sulfated polysaccharide that plays a critical role in a
range of different biological processes. Therapeutically, it is mostly commonly used as an …

[PDF][PDF] S3-leitlinie sepsis–prävention, diagnose, therapie und nachsorge

FM Brunkhorst, MA Weigand, M Pletz… - 2020 - publications.goettingen-research …
BeieinerSepsishandeltessichumeinelebens… Organdysfunktion ausgelöst durch eine
Infektion, die mit einer Regulationsstörung beim Wirt einhergeht. Ähnlich wie bei …

The role of HMGB1 in COVID‐19‐induced cytokine storm and its potential therapeutic targets: A review

S Wulandari, Hartono, T Wibawa - Immunology, 2023 - Wiley Online Library
Hyperinflammation characterized by elevated proinflammatory cytokines known as 'cytokine
storms' is the major cause of high severity and mortality seen in COVID‐19 patients. The …

[PDF][PDF] Diagnosis and management of heparin‐induced thrombocytopenia

DJ Arachchillage, J Thachil… - British Journal of …, 2024 - cancer-networks.com
The review of the guideline followed the standard BSH guidelines procedure. Following
review of the draft guideline by the BSH Haemostasis and Thrombosis Task Force and the …

ACE2-independent interaction of SARS-CoV-2 spike protein with human epithelial cells is inhibited by unfractionated heparin

LJ Partridge, L Urwin, MJH Nicklin, DC James… - Cells, 2021 - mdpi.com
Coronaviruses such as SARS-CoV-2, which is responsible for COVID-19, depend on virus
spike protein binding to host cell receptors to cause infection. The SARS-CoV-2 spike …