Breeders have traditionally improved plant varieties by selecting on the basis of phenotype.
Now restriction fragment length polymorphism (RFLP) linkage maps are being constructed …

For over 35 years, immunologists have divided T-helper (TH) cells into functional subsets. T-
helper type 1 (TH1) cells—long thought to mediate tissue damage—might be involved in the …

Publisher Summary Genetic markers are held for a detailed investigation of complex
questions in quantitative biology. The advent of DNA markers, greatly expanding the number …

T-cell receptor α-and β-chain genes were isolated from a class I major histocompatibility
complex-restricted cytotoxic T-cell clone and transferred by protoplast fusion into another …

Reproduction of bald eagles in northwestern Ontario declined from 1.26 young per breeding
area in 1966 to a low of 0.46 in 1974 and then increased to 1.12 in 1981. Residues of DDE …

Around the turn of the century, it was found that tumors of a particular mouse would grow
only in mice of the same inbred strain, The ability to transplant both neoplastic and normal …

The nonobese diabetic mouse is recognized as an important animal model for human
insulin-dependent diabetes mellitus. One of the components of susceptibility to this disease …

Recombination, together with mutation, generates the raw material of evolution, is essential
for reproduction and lies at the heart of all genetic analysis. Recent advances in our ability to …

Population genetic analysis of 15 restriction site polymorphisms demonstrates nonuniform
recombination within the human beta-globin gene cluster. These DNA polymorphisms show …

We have constructed a restriction fragment length polymorphism linkage map for the nuclear
genome of the flowering plant Arabidopsis thaliana. The map, containing 90 randomly …