Regulation of K-Cl cotransport: from function to genes

NC Adragna, MD Fulvio, PK Lauf - The Journal of membrane biology, 2004 - Springer
This review intends to summarize the vast literature on K-Cl cotransport (COT) regulation
from a functional and genetic viewpoint. Special attention has been given to the signaling …

Physiological significance of volume-regulatory transporters

WC O'Neill - American Journal of Physiology-Cell …, 1999 - journals.physiology.org
Research over the past 25 years has identified specific ion transporters and channels that
are activated by acute changes in cell volume and that serve to restore steady-state volume …

Investigating the effect of sterilisation methods on the physical properties and cytocompatibility of methyl cellulose used in combination with alginate for 3D-bioplotting …

E Hodder, S Duin, D Kilian, T Ahlfeld, J Seidel… - Journal of Materials …, 2019 - Springer
For both the incorporation of cells and future therapeutic applications the sterility of a
biomaterial must be ensured. However, common sterilisation techniques are intense and …

Influence of extracellular osmolarity and mechanical stimulation on gene expression of intervertebral disc cells

K Wuertz, JPG Urban, J Klasen… - Journal of …, 2007 - Wiley Online Library
Intervertebral discs (IVD) have a higher extracellular osmolarity than most other tissues;
moreover their osmolarity changes by around 25% during each diurnal cycle. In this study …

[HTML][HTML] The volume and morphology of chondrocytes within non-degenerate and degenerate human articular cartilage

PG Bush, AC Hall - Osteoarthritis and cartilage, 2003 - Elsevier
Objective: Cartilage swelling is an early event in osteoarthritis (OA). However, the response
of chondrocytes to increased tissue hydration is unknown. This work studied the volume and …

Sodium sensing in the interstitium and relationship to hypertension

J Titze, A Machnik - Current opinion in nephrology and …, 2010 - journals.lww.com
Sodium sensing in the interstitium and relationship to hyper... : Current Opinion in Nephrology
and Hypertension Sodium sensing in the interstitium and relationship to hypertension : Current …

The emerging chondrocyte channelome

R Barrett-Jolley, R Lewis, R Fallman… - Frontiers in …, 2010 - frontiersin.org
Chondrocytes are the resident cells of articular cartilage and are responsible for
synthesizing a range of collagenous and non-collagenous extracellular matrix …

Chondrocyte deformation within compressed agarose constructs at the cellular and sub-cellular levels

DA Lee, MM Knight, JF Bolton, BD Idowu… - Journal of …, 2000 - Elsevier
Mechanotransduction events in articular cartilage may be resolved into extracellular
components followed by intracellular signalling events, which finally lead to altered cell …

The osmotic sensitivity of isolated and in situ bovine articular chondrocytes

PG Bush, AC Hall - Journal of Orthopaedic Research, 2001 - Wiley Online Library
Articular chondrocytes experience changes to matrix hydration during both physiological
(static load) and pathophysiological (osteoarthrosis, OA) conditions. Such changes should …

The role of the membrane potential in chondrocyte volume regulation

R Lewis, KE Asplin, G Bruce, C Dart… - Journal of cellular …, 2011 - Wiley Online Library
Many cell types have significant negative resting membrane potentials (RMPs) resulting
from the activity of potassium‐selective and chloride‐selective ion channels. In excitable …