Immunotherapy of hepatocellular carcinoma

B Heinrich, C Czauderna, JU Marquardt - Oncology Research and …, 2018 - karger.com
Hepatocellular carcinoma (HCC) is one of the most deadly and rapidly evolving cancers
worldwide. The current systemic treatment strategies in advanced tumor stages remain …

Efficacy and security of tumor vaccines for hepatocellular carcinoma: a systemic review and meta-analysis of the last 2 decades

CL Han, YC Yan, LJ Yan, GX Meng, CC Yang… - Journal of Cancer …, 2023 - Springer
Background Tumor vaccines for hepatocellular carcinoma (HCC) is an area of intense
interest. Tremendous clinical trials have been conducted globally, but the efficacy and …

Intratumoral IL-12 gene therapy inhibits tumor growth in a HCC-Hu-PBL-NOD/SCID murine model

ZF Zhou, F Peng, JY Li, YB Ye - OncoTargets and therapy, 2019 - Taylor & Francis
Purpose This study aimed to evaluate the efficacy and safety of intratumoral IL-12 gene
therapy in an HCC-hu-PBL-NOD/SCID mouse model. Materials and methods The HCC …

[HTML][HTML] WIPI2 depletion inhibits the growth of hepatocellular carcinoma cells through the AMPK signaling pathway

C Liu, F Li, X Li, M Cao, G Feng… - Oncology …, 2020 - spandidos-publications.com
WD‑repeat domain phosphoinositide‑interacting protein 2 (WIPI2) is a protein that regulates
the assembly of multiprotein complexes by presenting a beta‑propeller platform for …

[HTML][HTML] Precision medicine for hepatocelluar carcinoma using molecular pattern diagnostics: results from a preclinical pilot study

R Agarwal, Y Cao, K Hoffmeier, N Krezdorn… - Cell Death & …, 2017 - nature.com
The aim of this study was to design a road map for personalizing cancer therapy in
hepatocellular carcinoma (HCC) by using molecular pattern diagnostics. As an exploratory …

B lymphocytes repress hepatic tumorigenesis but not development in Hras12V transgenic mice

K Wang, X Nie, Z Rong, T Fan, J Li… - … Journal of Cancer, 2017 - Wiley Online Library
Increasing reports show noninflammation underlying HCC, challenging our understanding
of the roles of the immune system in hepatocarcinogenesis. By exploring a mouse model of …

[PDF][PDF] Interim results from ongoing phase III placebo-controlled, randomized trial of hepcortespenlisimut-L for advanced hepatocellular carcinoma indication

AS Bourinbaiar, J Chinburen, P Batchuluun… - Hepatoma …, 2020 - pdfs.semanticscholar.org
Aim: We aimed to further investigate the role of hepcortespenlisimut-L (Hepko-V5 or V5), a
new oral immunotherapy developed by us, for hepatocellular carcinoma (HCC) indication …

Xenotransplante de tecido ovárico bovino como modelo para testar novas drogas, analisar a angiogénese, a depleção prematura ea dinâmica folicular

ARF Azevedo - 2019 - estudogeral.uc.pt
O processo de criopreservação de tecido ovárico é atualmente considerado como um dos
futuros métodos de eleição na preservação da fertilidade feminina. O tecido ovárico …