Environmental pollutants induce NLRP3 inflammasome activation and pyroptosis: roles and mechanisms in various diseases

Y Mou, W Liao, Y Liang, Y Li, M Zhao, Y Guo… - Science of The Total …, 2023 - Elsevier
Environmental pollution is changing with economic development. Most environmental
pollutants are characterized by stable chemical properties, strong migration, potential …

Rutin as neuroprotective agent: From bench to bedside

B Budzynska, C Faggio, M Kruk-Slomka… - Current medicinal …, 2019 - ingentaconnect.com
Flavonoids are major dietary constituents of plant-based food found ubiquitously in plant
kingdom where they are usually present in substantial amounts. Rutin is a flavonol-type …

Neuroprotective effect of naringin against cerebellar changes in Alzheimer's disease through modulation of autophagy, oxidative stress and tau expression: An …

HM Hassan, MR Elnagar, E Abdelrazik… - Frontiers in …, 2022 - frontiersin.org
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by gradual
cognitive decline. Strong antioxidants that inhibit free radicals, such as polyphenols, reduce …

[HTML][HTML] Effect of gallic acid on dementia type of Alzheimer disease in rats: electrophysiological and histological studies

S Hajipour, A Sarkaki, Y Farbood, A Eidi… - Basic and clinical …, 2016 - ncbi.nlm.nih.gov
Methods: Sixty-four adult male Wistar rats (300±20 g) were divided into 8 groups: 1) Control
(Cont); 2) AD; 3) Sham; 4–7) AD+ GA (50, 100, and 200 mg/kg for 10 days, orally) or vehicle …

Valorization of grape (Vitis vinifera) leaves for bioactive compounds: novel green extraction technologies and food-pharma applications

J Singh, P Rasane, R Kaur, H Kaur, R Garg… - Frontiers in …, 2023 - frontiersin.org
Grape leaves, scientifically known as Vitis vinifera, the primary by-product obtained after the
processing of grapes, are gathered in enormous amounts and disposed of as agricultural …

The anti-Alzheimer potential of Tamarindus indica: An in vivo investigation supported by in vitro and in silico approaches

AH Elmaidomy, UR Abdelmohsen, F Alsenani, HF Aly… - RSC …, 2022 - pubs.rsc.org
Tamarindus indica Linn.(Tamarind, F. Fabaceae) is one of the most widely consumed fruits
in the world. A crude extract and different fractions of T. indica (using n-hexane …

Therapeutic impact of grape leaves polyphenols on certain biochemical and neurological markers in AlCl3-induced Alzheimer's disease

IH Borai, MK Ezz, MZ Rizk, HF Aly… - Biomedicine & …, 2017 - Elsevier
Alzheimer's disease (AD) is a grave and prevailing neurodegenerative disease,
characterized by slow and progressive neurodegeneration in different brain regions …

Nutritional supplementation of gallic acid ameliorates Alzheimer-type hippocampal neurodegeneration and cognitive impairment induced by aluminum chloride …

B Ogunlade, SA Adelakun, JA Agie - Drug and chemical toxicology, 2022 - Taylor & Francis
Prolonged exposure to aluminum through occupational hazards or food/water intake has
been linked to the occurrence of Alzheimer's disease (AD). This study aimed at investigating …

ATP-sensitive potassium-channel inhibitor glibenclamide attenuates HPA axis hyperactivity, depression-and anxiety-related symptoms in a rat model of Alzheimer's …

MH Esmaeili, B Bahari, AA Salari - Brain research bulletin, 2018 - Elsevier
Affective disorders including depression and anxiety are among the most prevalent
behavioral abnormalities in patients with Alzheimer's disease (AD), which affect the quality …

[HTML][HTML] Troxerutin protects hippocampal neurons against amyloid beta-induced oxidative stress and apoptosis

F Farajdokht, M Amani, FM Bavil, A Alihemmati… - EXCLI …, 2017 - ncbi.nlm.nih.gov
Alzheimer's disease (AD) is an age-related neurodegenerative disease linked with
increased production and/or deposition of amyloid-beta (Aβ) in the brain. The aim of the …