The shared role of amyloid-β (Aβ) deposition in cerebral amyloid angiopathy (CAA) and
Alzheimer disease (AD) is arguably the clearest instance of crosstalk between …

The blood–brain barrier (BBB) plays a vital role in maintaining the specialized
microenvironment of the neural tissue. It separates the peripheral circulatory system from the …

The prevalence of dementia is increasing in our aging population at an alarming rate.
Because of the heterogeneity of clinical presentation and complexity of disease …

Background and Purpose—This scientific statement provides an overview of the evidence
on vascular contributions to cognitive impairment and dementia. Vascular contributions to …

Amyloid-related imaging abnormalities (ARIA) are adverse events reported in Alzheimer's
disease trials of anti-amyloid beta (Aβ) therapies. This review summarizes the existing …

Cerebral amyloid angiopathy (CAA) involves cerebrovascular amyloid deposition and is
classified into several types according to the amyloid protein involved. Of these, sporadic …

Amyloid imaging related abnormalities (ARIA) have now been reported in clinical trials with
multiple therapeutic avenues to lower amyloid-β burden in Alzheimer's disease (AD). In …

Cerebral amyloid angiopathy (CAA) results from deposition of β‐amyloid in the media and
adventitia of small arteries and capillaries of the leptomeninges and cerebral cortex and is a …

Importance Cerebral amyloid angiopathy–related inflammation (CAA-ri) is an important
diagnosis to reach in clinical practice because many patients with the disease respond to …

Sporadic cerebral amyloid angiopathy (CAA) is a common age related cerebral small vessel
disease, characterised by progressive deposition of amyloid-β (Aβ) in the wall of small to …