Although the social role of oxytocin came to light due to sex-specific interactions such as
mother–offspring bonding, current understanding of sex differences in the effects of oxytocin …

Social rewards are strong drivers of behavior and fundamental to well-being, yet there is a
lack of consensus regarding what actually defines a reward as “social.” Because a …

Introduction: Anxiety disorders are prevalent mental conditions characterized by
exaggerated anxious arousal and threat reactivity. Animal and human studies suggest an …

Background Rodent models and pharmacological neuroimaging studies in humans have
been used to test novel pharmacological agents to reduce fear. However, these strategies …

Over the last decade, a number of clinical trials have reported effects of chronic treatment
with intranasal oxytocin on autistic symptoms but with inconsistent findings. Autism is a …

The neuropeptide oxytocin is a key modulator of social-emotional behavior and its intranasal
administration can influence the functional connectivity of brain networks involved in the …

Background There is a need for novel analgesics with favorable risk to benefit profiles.
Oxytocin has recently gained attention for its potential analgesic properties. Aim The aim of …

Neuropathic pain is difficult to cure and is often accompanied by emotional and
psychological changes. Exploring the mechanisms underlying neuropathic pain will help to …

A synaptic sexual dimorphism is relevant in the context of multiple neurodevelopmental,
neurodegenerative, and neuropsychiatric disorders. Many of these disorders show a …

The ability to successfully regulate negative emotions such as fear and anxiety is vital for
mental health. Intranasal administration of the neuropeptide oxytocin (OXT) has been shown …