Paracoccidioides Spp.: Virulence Factors and Immune‐Evasion Strategies

E Camacho, GA Niño-Vega - Mediators of inflammation, 2017 - Wiley Online Library
Paracoccidioides spp. are dimorphic fungal pathogens responsible for one of the most
relevant systemic mycoses in Latin America, paracoccidioidomycosis (PCM). Their exact …

Omics approaches for understanding biogenesis, composition and functions of fungal extracellular vesicles

D Zamith-Miranda, R Peres da Silva… - Frontiers in …, 2021 - frontiersin.org
Extracellular vesicles (EVs) are lipid bilayer structures released by organisms from all
kingdoms of life. The diverse biogenesis pathways of EVs result in a wide variety of physical …

Virulence and Antifungal Susceptibility of Microsporum canis Strains from Animals and Humans

CI Aneke, W Rhimi, V Hubka, D Otranto, C Cafarchia - Antibiotics, 2021 - mdpi.com
The enzymatic and antifungal profiles of dermatophytes play an important role in causing
infections in humans and animals. This study aimed to assess the virulence factors …

Metabolic Plasticity and Virulence-Associated Factors of Sporothrix brasiliensis Strains Related to Familiar Outbreaks of Cat-to-Human Transmitted Sporotrichosis

D Corrêa-Junior, IB de Andrade, V Alves… - Journal of Fungi, 2023 - mdpi.com
Sporothrix brasiliensis is the main agent of zoonotic sporotrichosis transmitted by domestic
cats in South America. In humans, sporotrichosis commonly presents with cutaneous or …

In vitro and in silico analysis reveals antifungal activity and potential targets of curcumin on Paracoccidioides spp.

OB Rocha, L do Carmo Silva… - Brazilian Journal of …, 2021 - Springer
The search for new compounds with activity against Paracoccidioides, etiologic agents of
Paracoccidioidomycosis (PCM), is extremely necessary due to the current scenario of the …

Enzyme activity and expression of catalases in response to oxidative stress in Sporothrix schenckii

KM Román-Casiano, AL Martínez-Rocha… - Microbial …, 2021 - Elsevier
Sporothrix schenckii is a dimorphic fungus, pathogenic to humans and animals, which is
usually infective in the yeast form. Reactive oxygen species (ROS) play an important role in …

Differential Metabolism of a Two-Carbon Substrate by Members of the Paracoccidioides Genus

LC Baeza, FR Da Mata, LL Pigosso, M Pereira… - Frontiers in …, 2017 - frontiersin.org
The genus Paracoccidioides comprises known fungal pathogens of humans and can be
isolated from different infection sites. Metabolic peculiarities in different members of the …

3-Phenacylideneoxindoles as a New Class of Antifungal Compounds Against Paracoccidioides Spp.

LC Silva, RF dos Santos Filho, AA de Oliveira… - Future …, 2023 - Taylor & Francis
Aims: Considering the need to identify new compounds with antifungal action, the activity of
five 3-phenacylideneoxindoles compounds was evaluated. Materials & methods: The …

Down-regulation of TUFM impairs host cell interaction and virulence by Paracoccidioides brasiliensis

CM Marcos, G Tamer, HC De Oliveira, PA Assato… - Scientific reports, 2019 - nature.com
The genus Paracoccidioides consist of dimorphic fungi geographically limited to the
subtropical regions of Latin America, which are responsible for causing deep systemic …

Sequencing and gene expression analysis of catalase genes in Antarctic fungal strain Penicillium griseofulvum P29

G Stoyancheva, V Dishliyska, J Miteva‐Staleva… - Polar Biology, 2022 - Springer
Catalases are key antioxidant enzymes in aerobic organisms, including fungi that mitigate
oxidative stress by detoxification of cellular hydrogen peroxide. Filamentous fungi possess …