The hypothalamo-pituitary-adrenal (HPA) axis is one of the main components of the stress
system. Maintenance of normal physiological events, which include stress responses to …

Abstract Although coronavirus disease 2019 (COVID-19) mainly involves the lungs, it also
affects many systems. The hypothalamic/pituitary axis is vulnerable to hypoxia …

Introduction The prevalence of pituitary dysfunction is high following aneurysmal
subarachnoid hemorrhage (aSAH) and when occurs it may contribute to residual symptoms …

Context Studies on 24-h cortisol secretion are rare. The impact of sex, age and adiposity on
cortisol levels, often restricted to one or a few samples, are well recognized, but conflicting …

Context Recent studies suggest using lower GH cut-points for the glucagon stimulation test
(GST) in diagnosing adult GH deficiency (GHD), especially in obese patients. There are …

SARS-CoV-2 may affect the hypothalamic-pituitary axis and pituitary dysfunction may occur.
Therefore, we investigated neuroendocrine changes, in particular, secondary adrenal …

Establishment of revised diagnostic cut-offs for adrenal laboratory investigation using the new
Roche Diagnostics Elecsys® Cortisol II assay Establishment of revised diagnostic cut-offs for …

Context Diagnosis of secondary adrenal insufficiency and GH deficiency requires evaluation
by dynamic stimulation tests in most cases. Although insulin tolerance test (ITT) is accepted …

Summary Objective The short Synacthen test (SST) is widely used as alternative test to the
insulin tolerance test (ITT) to investigate central adrenal insufficiency (CAI), but the …

Diagnosis of adrenal insufficiency requires evaluation by dynamic stimulation tests. The
insulin tolerance test (ITT) is accepted as the gold-standard test for the evaluation of …