Brain organoids, or cerebral organoids, have become widely used to study the human brain
in vitro. As pluripotent stem cell-derived structures capable of self-organization and …

Recording from a large neuronal population of neurons is a crucial challenge to unravel how
information is processed by the brain. In this review, we highlight the recent advances made …

Spike sorting is a crucial step in electrophysiological studies of neuronal activity. While many
spike sorting packages are available, there is little consensus about which are most …

Highlights•Novel devices are posing challenges to existing spike sorting pipelines.•Spike
sorting methodology is expanding to handle thousands to millions of neurons.•Multi-stage …

Modern recording technologies now enable simultaneous recording from large numbers of
neurons. This has driven the development of new statistical models for analyzing and …

Spike sorting is one of the most important data analysis problems in neurophysiology. The
precision in all steps of the spike-sorting procedure critically affects the accuracy of all …

When recording neural activity from extracellular electrodes, both in vivo and in vitro, spike
sorting is a required and very important processing step that allows for identification of single …

Many people suffer from movement disability due to amputation or neurological diseases.
Fortunately, with modern neurotechnology now it is possible to intercept motor control …

Objective. Spike sorting is a set of techniques used to analyze extracellular neural
recordings, attributing individual spikes to individual neurons. This field has gained …

The shape of extracellularly recorded action potentials is a product of several variables,
such as the biophysical and anatomical properties of the neuron and the relative position of …