Rhinitis and asthma: evidence for respiratory system integration

A Togias - Journal of Allergy and Clinical Immunology, 2003 - Elsevier
The vast majority of patients with asthma have rhinitis, and rhinitis is a major independent
risk factor for asthma in cross-sectional and longitudinal studies. The relationships between …

Allergic rhinitis and asthma: how important is the link?

J Corren - Journal of allergy and clinical immunology, 1997 - Elsevier
Dysfunction of the upper and lower airways frequently coexist, and they appear to share key
elements of pathogenesis. Data from epidemiologic studies indicate that nasal symptoms …

Rhinitis and onset of asthma: a longitudinal population-based study

R Shaaban, M Zureik, D Soussan, C Neukirch… - The Lancet, 2008 - thelancet.com
Background A close relation between asthma and allergic rhinitis has been reported by
several epidemiological and clinical studies. However, the nature of this relation remains …

Nasal allergen provocation induces adhesion molecule expression and tissue eosinophilia in upper and lower airways

GJ Braunstahl, SE Overbeek, A KleinJan… - Journal of Allergy and …, 2001 - Elsevier
Background: Allergic rhinitis (AR) and asthma are characterized by means of a similar
inflammatory process in which eosinophils are important effector cells. The migration of …

Allergic rhinobronchitis: the asthma–allergic rhinitis link

FER Simons - Journal of allergy and clinical immunology, 1999 - Elsevier
Allergic rhinitis and asthma are linked by epidemiologic, histologic, physiologic, and
immunopathologic characteristics and by a common therapeutic approach …

Allergic rhinitis: systemic inflammation and implications for management

L Borish - Journal of allergy and clinical immunology, 2003 - Elsevier
Allergic rhinitis triggers a systemic increase of inflammation. Within minutes of allergen
exposure, immune cells release histamine, proteases, cysteinyl leukotrienes …

Allergic rhinitis, rhinosinusitis, and asthma: one airway disease

C Bachert, AM Vignola, P Gevaert… - Immunology and …, 2004 - immunology.theclinics.com
Asthma and allergies, including rhinoconjunctivitis and atopic dermatitis, are common
throughout the world, with a high burden of morbidity and cost. The nasal and bronchial …

Changes in bronchial responsiveness following nasal provocation with allergen

J Corren, AD Adinoff, CG Irvin - Journal of allergy and clinical immunology, 1992 - Elsevier
The relationship between upper airway inflammation and asthma is controversial. In the
current study, we sought to investigate the relationship between allergic rhinitis and lower …

Viruses as precipitants of asthma symptoms. I. Epidemiology

PK Pattemore, SL Johnston… - Clinical and Experimental …, 2006 - pmc.ncbi.nlm.nih.gov
Christopher Robin had wheezles and sneezles, they bundled him into his bed. They gave
him what goes with a cold in the nose, and some more for a cold in the head. They …

Segmental bronchoprovocation in allergic rhinitis patients affects mast cell and basophil numbers in nasal and bronchial mucosa

GJ Braunstahl, SE Overbeek, WJ Fokkens… - American journal of …, 2001 - atsjournals.org
Mast cells and basophils are cells that play an important role in the initiation and control of
allergic inflammation in asthma and rhinitis. This study was undertaken to determine the …