Basic principles of photodynamic therapy

IJ Macdonald, TJ Dougherty - Journal of porphyrins and …, 2001 - World Scientific
The therapeutic use of light, as we know it, begins in 1900 when Raab reported that the
combination of acridine orange and light could destroy living organisms (paramecium)[1]. In …

[HTML][HTML] Photophysical and photobiological processes in the photodynamic therapy of tumours

M Ochsner - Journal of Photochemistry and Photobiology B: Biology, 1997 - Elsevier
Photodynamic therapy (PDT) is an innovative and attractive modality for the treatment of
small and superficial tumours. PDT, as a multi-modality treatment procedure, requires both a …

[HTML][HTML] State of the art in the delivery of photosensitizers for photodynamic therapy

YN Konan, R Gurny, E Allémann - Journal of Photochemistry and …, 2002 - Elsevier
In photodynamic therapy, one of the problems limiting the use of many photosensitizers (PS)
is the difficulty in preparing pharmaceutical formulations that enable their parenteral …

Photosensitizers: therapy and detection of malignant tumors

TJ Dougherty - Photochemistry and Photobiology, 1987 - Wiley Online Library
Advances in the use of photosensitizers for detection and treatment of malignant tumors
during the previous reviews in this journal have been mainly in the areas of development of …

Targeted photodynamic therapy via receptor mediated delivery systems

WM Sharman, JE van Lier, CM Allen - Advanced drug delivery reviews, 2004 - Elsevier
Targeted photodynamic therapy (PDT) offers the opportunity of enhancing photodynamic
efficiency by directly targeting diseased cells and tissues. While antibody-conjugates have …

Advances in liposome-encapsulated phthalocyanines for photodynamic therapy

J Rak, M Kabesova, J Benes, P Pouckova, D Vetvicka - Life, 2023 - mdpi.com
This updated review aims to describe the current status in the development of liposome-
based systems for the targeted delivery of phthalocyanines for photodynamic therapy (PDT) …

Designing photosensitizers for photodynamic therapy: strategies, challenges and promising developments

MJ Garland, CM Cassidy, D Woolfson… - Future medicinal …, 2009 - Taylor & Francis
Photodynamic therapy (PDT) and photodynamic antimicrobial chemotherapy (PACT) are
techniques that combine the effects of visible light irradiation with subsequent biochemical …

Terapia fotodinâmica: princípios, potencial de aplicação e perspectivas

AEH Machado - Química Nova, 2000 - SciELO Brasil
Photodynamic Therapy (PDT) has been designated as a promising new modality in the
treatment of cancer and other diseases since the early 1980s. It has been used with success …

Drug delivery systems for phthalocyanines for photodynamic therapy

J Rak, P Pouckova, J Benes, D Vetvicka - Anticancer research, 2019 - ar.iiarjournals.org
The focus of this review is to describe the state-of-art in the development of innovative drug
delivery systems for phthalocyanines as photosensitizers for photodynamic therapy (PDT) …

New trends in photobiology: On the mechanism of the tumour-localising effect in photodynamic therapy

MR Hamblin, EL Newman - Journal of Photochemistry and Photobiology B …, 1994 - Elsevier
The proposed mechanisms by which tumours concentrate photosensitisers are reviewed.
Tumour-associated macrophages have been shown by others to accumulate up to nine …