Monoclonal antibodies (mAbs) are often selected from antigen-specific single B cells
derived from different hosts, which are notably short-lived in ex vivo culture conditions and …

The route of administration of a therapeutic agent has a substantial impact on its success.
Therapeutic antibodies are usually administered systemically, either directly by intravenous …

Somatic hypermutation (SHM) drives affinity maturation and continues over months in SARS-
CoV-2-neutralizing antibodies (nAbs). However, several potent SARS-CoV-2 antibodies …

Arthropod-borne viruses represent a crucial public health threat. Current arboviral serology
assays are either labor intensive or incapable of distinguishing closely related viruses, and …

Dengue is the most common arboviral disease caused by one of four distinct but closely
related dengue viruses (DENV) and places significant economic and public health burdens …

Dengue is the most common viral infection spread by mosquitoes, prevalent in tropical
countries. The acute dengue virus (DENV) infection is a benign and primarily febrile illness …

The isolation of single monoclonal antibodies (mAbs) against a given antigen was only
possible with the introduction of the hybridoma technology, which is based on the fusion of …

Dengue virus (DENV) is a global health threat causing about half of the worldwide
population to be at risk of infection, especially the people living in tropical and subtropical …

Infusion of broadly neutralizing antibodies (bNAbs) has shown promise as an alternative to
anti-retroviral therapy against HIV. A key challenge is to suppress viral escape, which is …

Flavivirus detection in humans and mosquito reservoirs has been an important issue since it
can cause a variety of illnesses and could represent a health problem in geographical zones …