Pharmacological properties of chalcones: a review of preclinical including molecular mechanisms and clinical evidence

B Salehi, C Quispe, I Chamkhi, N El Omari… - Frontiers in …, 2021 - frontiersin.org
Chalcones are among the leading bioactive flavonoids with a therapeutic potential
implicated to an array of bioactivities investigated by a series of preclinical and clinical …

The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research

JB McAlpine, SN Chen, A Kutateladze… - Natural product …, 2019 - pubs.rsc.org
Covering: up to 2018 With contributions from the global natural product (NP) research
community, and continuing the Raw Data Initiative, this review collects a comprehensive …

Butein in health and disease: A comprehensive review

G Padmavathi, NK Roy, D Bordoloi, F Arfuso, S Mishra… - Phytomedicine, 2017 - Elsevier
Background The risk of suffering from many chronic diseases seems to have made no
improvement despite the advancement in medications available in the modern world …

Brazilian arnicas: Bioactive compounds, pharmacological properties, potential use and clinical applications

BM Marinho, CH Lescano, SHS Santos - Phytochemistry Reviews, 2024 - Springer
Brazilian arnicas belong to the Asteraceae family and can be mainly found in the Brazilian
biome Cerrado (savanna) but also Caatinga, Atlantic Forest, Pampa, Pantanal, and …

The chemotherapeutic potential of chalcones against leishmaniases: a review

N Tajuddeen, MB Isah, MA Suleiman… - International journal of …, 2018 - Elsevier
Leishmaniases are endemic diseases in tropical and sub-tropical regions of the world and
are considered by the World Health Organization (WHO) to be among the six most important …

Hydroxylated Cinnamates Enhance Tomato Resilience to Alternaria alternata, the Causal Agent of Early Blight Disease, and Stimulate Growth and Yield Traits

Y Nehela, YSA Mazrou, NA Taha, AA Elzaawely… - Plants, 2023 - mdpi.com
The important vegetable crop, tomato, is challenged with numerous abiotic and biotic
stressors, particularly the newly emerged fungicide-resistant strains of phytopathogenic …

Trypanocidal Mechanism of Action and in silico Studies of p-Coumaric Acid Derivatives

SP Lopes, YP Castillo, ML Monteiro… - International journal of …, 2019 - mdpi.com
Trypanosoma species are responsible for chronic and systemic infections in millions of
people around the world, compromising life quality, and family and government budgets …

Asteraceae plants as sources of compounds against leishmaniasis and Chagas disease

RN Moraes Neto, RFB Setúbal, TMM Higino… - Frontiers in …, 2019 - frontiersin.org
Leishmaniasis and Chagas disease cause great impact on social and economic aspects of
people living in developing countries. The treatments for these diseases are based on the …

Bioactivity and molecular docking studies of derivatives from cinnamic and benzoic acids

Y Perez-Castillo, TC Lima, AR Ferreira… - BioMed research …, 2020 - Wiley Online Library
Over the last decade, there has been a dramatic increase in the prevalence and gravity of
systemic fungal diseases. This study aimed therefore at evaluating the antifungal potential of …

Structure− activity relationships of cinnamate ester analogues as potent antiprotozoal agents

FA Bernal, M Kaiser, B Wünsch, TJ Schmidt - ChemMedChem, 2020 - Wiley Online Library
Protozoal infections are still a global health problem, threatening the lives of millions of
people around the world, mainly in impoverished tropical and sub‐tropical regions. Thus, in …