Anhedonia is a core symptom of major depressive disorder (MDD), the neurobiological
mechanisms of which remain poorly understood. Despite decades of speculation regarding …

Previous meta-analyses of structural MRI studies have shown diffuse cortical and sub-
cortical abnormalities in unipolar depression. However, the presence of duplicate …

Context Although differences in clinical characteristics exist between major depressive
disorder (MDD) and bipolar disorder (BD), consistent structural brain abnormalities that …

Both major depressive disorder and bipolar disorder are the subject of a voluminous
imaging and genetics literature. Here, we attempt a comprehensive review of MRI and …

Objective The authors sought to investigate whether the structural development of limbic,
striatal, and prefrontal regions that are critically implicated in the pathophysiology of …

BackgroundAbnormalities in cortico-striatal-pallidal-thalamic (CSPT) circuits have been
implicated in major depressive disorder (MDD). However, the robustness of these findings …

Child and adolescent psychiatric neuroimaging research typically lags behind similar
advances in adult disorders. While the pediatric depression imaging literature is less …

The unique neuroanatomical underpinnings of internalizing symptoms and impulsivity
during childhood are not well understood. In this study, we examined associations of brain …

Objective Children of parents with depression are two to three times more likely to develop
major depressive disorder than children without parental history; however, subcortical brain …

Objective Although depression and anxiety often have distinct etiologies, they frequently co-
occur in adolescence. Recent initiatives have underscored the importance of developing …