Systems pharmacology for investigation of the mechanisms of action of traditional Chinese medicine in drug discovery

W Zhang, Y Huai, Z Miao, A Qian… - Frontiers in pharmacology, 2019 - frontiersin.org
As a traditional medical intervention in Asia and a complementary and alternative medicine
in western countries, traditional Chinese medicine (TCM) has attracted global attention in …

Upregulation of melanogenesis and tyrosinase activity: potential agents for vitiligo

C Niu, HA Aisa - Molecules, 2017 - mdpi.com
Melanin, the compound primarily responsible in humans for hair, eye and skin pigmentation,
is produced by melanocytes through a complicated process called melanogenesis that is …

Mass spectrometry‐driven drug discovery for development of herbal medicine

A Zhang, H Sun, X Wang - Mass spectrometry reviews, 2018 - Wiley Online Library
Herbal medicine (HM) has made a major contribution to the drug discovery process with
regard to identifying products compounds. Currently, more attention has been focused on …

Butein in health and disease: A comprehensive review

G Padmavathi, NK Roy, D Bordoloi, F Arfuso, S Mishra… - Phytomedicine, 2017 - Elsevier
Background The risk of suffering from many chronic diseases seems to have made no
improvement despite the advancement in medications available in the modern world …

Systematic elucidation of the mechanism of geraniol via network pharmacology

YF Zhang, Y Huang, YH Ni, ZM Xu - Drug design, development and …, 2019 - Taylor & Francis
Background Geraniol is an acyclic monoterpene alcohol, which is extracted from the
ethereal oils of aromatic plants. A systematic analysis of its mechanism of action has not yet …

Herb‐functionalized chronic wound dressings for enhancing biological functions: multiple flavonoids coordination driven strategy

M Sun, S Peng, C Zhao, J Huang, J Xia… - Advanced Functional …, 2022 - Wiley Online Library
Developing a hydrogel‐based multiple plant flavonoids dressing can synergistically assist
chronic wound closure and enable superior solubility and optimal therapeutic efficacy of …

Systems Pharmacology Dissection of Multi-Scale Mechanisms of Action of Huo-Xiang-Zheng-Qi Formula for the Treatment of Gastrointestinal Diseases

M Zhao, Y Chen, C Wang, W Xiao, S Chen… - Frontiers in …, 2019 - frontiersin.org
Multi-components Traditional Chinese Medicine (TCM) treats various complex diseases
(multi-etiologies and multi-symptoms) via herbs interactions to exert curative efficacy with …

Recent developments and emerging trends of mass spectrometry for herbal ingredients analysis

A Zhang, H Sun, G Yan, X Wang - TrAC Trends in Analytical Chemistry, 2017 - Elsevier
Herbal preparation has recently increased health awareness and its efficacy is brought
about by the multi-constituents. Therefore, the application of mass spectrometry (MS) in …

Plant-derived compounds as promising therapeutics for vitiligo

Y Pang, S Wu, Y He, Q Nian, J Lei, Y Yao… - Frontiers in …, 2021 - frontiersin.org
Vitiligo is the most common depigmenting disorder characterized by white patches in the
skin. The pathogenetic origin of vitiligo revolves around autoimmune destruction of …

Research progress on targeted antioxidant therapy and vitiligo

J Zhang, W Hu, P Wang, Y Ding… - … Medicine and Cellular …, 2022 - Wiley Online Library
Vitiligo is a common acquired depigmenting disease characterized by the loss of functional
melanocytes and epidermal melanin. Vitiligo has a long treatment cycle and slow results …