Nuclear magnetic resonance (NMR) spectroscopy is a well-established method for
analyzing protein structure, interaction, and dynamics at atomic resolution and in various …

A detailed knowledge of the complex processes that make cells and organisms alive is
fundamental in order to understand diseases and to develop novel drugs and therapeutic …

A plethora of studies indicate that iron metabolism is dysregulated in Parkinson's disease
(PD). The literature reveals well-documented alterations consistent with established dogma …

Cu/Zn superoxide dismutase (SOD1) is a frontline antioxidant enzyme catalysing superoxide
breakdown and is important for most forms of eukaryotic life. The evolution of aerobic …

NMR spectroscopy has been applied to cells and tissues analysis since its beginnings, as
early as 1950. We have attempted to gather here in a didactic fashion the broad diversity of …

In-cell NMR can investigate protein conformational changes at atomic resolution, such as
those changes induced by drug binding or chemical modifications, directly in living human …

Conspectus Cellular structural biology methods are needed to characterize biological
processes at atomic resolution in the physiological environment of the cell. Toward this goal …

In-cell NMR spectroscopy is a powerful approach to study protein structure and function in
the native cellular environment. It provides precious insights into the folding, maturation …

In-cell nuclear magnetic resonance (NMR) is a method to provide the structural information
of a target at an atomic level under physiological conditions and a full view of the …

Ischemic heart disease (IHD) is a significant global health concern, resulting in high rates of
mortality and disability among patients. Although coronary blood flow reperfusion is a key …