Abstract Since Banting and Best isolated insulin in the 1920s, dramatic progress has been
made in the treatment of type 1 diabetes mellitus (T1DM). However, dose titration and timely …

In silico simulation studies using 5807 virtual patients with insulin dependent diabetes have
been conducted to estimate the risk and efficacy with the closed-loop 780G pump when …

Background No meta-analysis has analysed efficacy and safety of fast-acting aspart insulin
(FIAsp) with insulin pump in type 1 diabetes mellitus (T1DM). Methods Electronic databases …

Background: Computer simulators of human metabolism are powerful tools to design and
validate new diabetes treatments. However, these platforms are often limited in the diversity …

The use of biomaterials to enable and enhance life-saving therapies in medicine has its
documented roots in the 1600s. Historically drugs were administered systemically for acute …

Insulin has been utilized in the treatment of type 1 diabetes (T1D) for 100 years. While there
is still no cure for T1D, insulin administration has undergone a remarkable evolution which …

Control affine assumptions, human inputs are external disturbances, in certified safe
controller synthesis approaches are frequently violated in operational deployment under …

Résumé Ces dernières années, plusieurs analogues ultra-rapides de l'insuline ont été
développés afin de réduire la durée d'absorption sous-cutanée de l'insuline et améliorer …

Background Insulin icodec is a novel basal insulin analog intended for once‐weekly
administration. The aim of this phase 2 trial was to investigate the efficacy and safety of …

Высокая вариабельность гликемии (ВГ) оказывает значительное влияние на
прогрессирование осложнений у больных сахарным диабетом (СД). В ходе работы при …