Functional diversity of astrocytes in neural circuit regulation

LB Haim, DH Rowitch - Nature Reviews Neuroscience, 2017 - nature.com
Although it is well established that all brain regions contain various neuronal subtypes with
different functions, astrocytes have traditionally been thought to be homogenous. However …

Astrocyte heterogeneity: an underappreciated topic in neurobiology

Y Zhang, BA Barres - Current opinion in neurobiology, 2010 - Elsevier
Astrocytes, one of the most numerous types of cells in the central nervous system, are crucial
for potassium homeostasis, neurotransmitter uptake, synapse formation, regulation of blood …

[HTML][HTML] Glial fibrillary acidic protein (GFAP): modulation by growth factors and its implication in astrocyte differentiation

FCA Gomes, D Paulin, V Moura Neto - Brazilian journal of medical …, 1999 - SciELO Brasil
Intermediate filament (IF) proteins constitute an extremely large multigene family of
developmentally and tissue-regulated cytoskeleton proteins abundant in most vertebrate cell …

Structural remodeling of astrocytes in the injured CNS

D Sun, TC Jakobs - The Neuroscientist, 2012 - journals.sagepub.com
Astrocytes respond to all forms of CNS insult and disease by becoming reactive, a
nonspecific but highly characteristic response that involves various morphological and …

Glial cell extracellular matrix: boundaries for axon growth in development and regeneration

MT Fitch, J Silver - Cell and tissue research, 1997 - Springer
Astrocytes and other glia in the central nervous system are now thought to produce
molecules that negatively modulate axon growth, thereby influencing axon pathfinding in …

Membrane elastic properties and cell function

B Pontes, Y Ayala, ACC Fonseca, LF Romao… - PloS one, 2013 - journals.plos.org
Recent studies indicate that the cell membrane, interacting with its attached cytoskeleton, is
an important regulator of cell function, exerting and responding to forces. We investigate this …

Emerging roles for TGF-β1 in nervous system development

FCA Gomes, V de Oliveira Sousa, L Romão - International Journal of …, 2005 - Elsevier
Transforming growth factor betas (TGF-βs) are known as multifunctional growth factors,
which participate in the regulation of key events of development, disease and tissue repair …

Neuroinflammation and glial phenotypic changes in alpha-synucleinopathies

V Refolo, N Stefanova - Frontiers in cellular neuroscience, 2019 - frontiersin.org
The role of neuroinflammation has been increasingly recognized in the field of
neurodegenerative diseases. Many studies focusing on the glial cells involved in the …

Isoquercitrin suppresses colon cancer cell growth in vitro by targeting the Wnt/β-catenin signaling pathway

NG Amado, D Predes, BF Fonseca… - Journal of Biological …, 2014 - ASBMB
Flavonoids are plant-derived polyphenolic molecules that have potential biological effects
including anti-oxidative, anti-inflammatory, anti-viral, and anti-tumoral effects. These effects …

Heterogeneity in synaptogenic profile of astrocytes from different brain regions

AS Buosi, I Matias, APB Araujo, C Batista… - Molecular …, 2018 - Springer
Astrocytes, the most abundant glial cells in the central nervous system (CNS), comprise a
heterogeneous population of cells. However, how this heterogeneity impacts their function …