Current advances in lipid nanosystems intended for topical and transdermal drug delivery applications
N Akombaetwa, AB Ilangala, L Thom, PB Memvanga… - Pharmaceutics, 2023 - mdpi.com
Skin delivery is an exciting and challenging field. It is a promising approach for effective drug
delivery due to its ease of administration, ease of handling, high flexibility, controlled …
delivery due to its ease of administration, ease of handling, high flexibility, controlled …
[HTML][HTML] Augmented glycerosomes as a promising approach against fungal ear infection: Optimization and microbiological, ex vivo and in vivo assessments
In the current study, voriconazole (VCZ) augmented glycerosomes were optimized for topical
otomycosis management according to a 2 3 factorial design, employing a thin film hydration …
otomycosis management according to a 2 3 factorial design, employing a thin film hydration …
Syringeable atorvastatin loaded eugenol enriched PEGylated cubosomes in-situ gel for the intra-pocket treatment of periodontitis: statistical optimization and clinical …
Atorvastatin calcium (ATV) is a well-known anti-hyperlipidemic drug currently being
recognized for possessing an anti-inflammatory effect. Introducing it as a novel remedy for …
recognized for possessing an anti-inflammatory effect. Introducing it as a novel remedy for …
[PDF][PDF] HYDROGEL-BASED DELIVERY SYSTEMS FOR TOPICAL ANTIFUNGAL THERAPY: A REVIEW.
Fungal skin infections are a significant global health concern, with a high prevalence,
recurrence, and economic burden. Traditional antifungal therapies, such as creams and oral …
recurrence, and economic burden. Traditional antifungal therapies, such as creams and oral …
Engineered lecithin-based proniosomes for enhanced trans-tympanic permeation: In vitro, microbiological, ex vivo and in vivo evaluation
Otitis media is an acute illness that specifically targets the middle ear. It affects around one-
third of the pediatric population in the US. This study aimed to develop lecithin-based …
third of the pediatric population in the US. This study aimed to develop lecithin-based …
[HTML][HTML] Development of Glycerosomal pH Triggered In Situ Gelling System to Ameliorate the Nasal Delivery of Sulpiride for Pediatric Psychosis
MM Shahien, A Alshammari, S Ibrahim, EH Ahmed… - Gels, 2024 - mdpi.com
Sulpiride (Sul) is a medication that blocks dopamine D2 receptors. It is used to treat
gastrointestinal disturbances and has antipsychotic effects depending on the dose given …
gastrointestinal disturbances and has antipsychotic effects depending on the dose given …
Atorvastatin loaded lecithin-coated zein nanoparticles based thermogel for the intra-articular management of osteoarthritis: in-silico, in-vitro, and in-vivo studies
Purpose Up-to-date literature offers limited data about utilizing atorvastatin calcium (ATV) as
a promising chondroprotective agent in osteoarthritis (OA). So, this study aims to develop a …
a promising chondroprotective agent in osteoarthritis (OA). So, this study aims to develop a …
Tailoring Risperidone-Loaded Glycethosomal In Situ Gels Using Box–Behnken Design for Treatment of Schizophrenia-Induced Rats via Intranasal Route
MH Abdallah, HES El-Horany, HM El-Nahas… - Pharmaceutics, 2023 - mdpi.com
Schizophrenic patients often face challenges with adherence to oral regimens. The study
aimed to highlight the potentiality of intranasal ethanol/glycerin-containing lipid …
aimed to highlight the potentiality of intranasal ethanol/glycerin-containing lipid …
Optimizing nutraceutical-loaded trehalosomes in-situ gel for diabetic cataract management: Comprehensive in vitro and in vivo evaluations
This study aimed to develop Baicalin-loaded trehalosomes in situ gel (BA-THs-ISG) for the
treatment of cataract, a degenerative eye condition that requires innovative approaches to …
treatment of cataract, a degenerative eye condition that requires innovative approaches to …
Statistically-Based Optimization of Verapamil Hydrochloride Loaded Gastroretentive Alginate Beads
O Objectives: A gastroretentive drug delivery system is one of many oral drug delivery
systems developed to improve drug bioavailability and control drug release. It allows …
systems developed to improve drug bioavailability and control drug release. It allows …