Clinicopathological and prognostic values of telomerase reverse transcriptase (TERT) promoter mutations in ovarian clear cell carcinoma for predicting tumor …

H Yoo, HS Kim - Cancer genomics & proteomics, 2023 - cgp.iiarjournals.org
Background/Aim: A small subset of patients with ovarian clear cell carcinoma (OCCC)
harbors telomerase reverse transcriptase promoter (TERTp) mutations. We aimed to analyze …

RAD51 restricts DNA over-replication from re-activated origins

S Muñoz, E Blanco-Romero, D González-Acosta… - The EMBO …, 2024 - embopress.org
Eukaryotic cells rely on several mechanisms to ensure that the genome is duplicated
precisely once in each cell division cycle, preventing DNA over-replication and genomic …

Chromatin licensing and DNA replication factor 1 as a potential prognostic and diagnostic biomarker for gastric cancer

S Wang, M Cui, N Zhou, M Tong, S Wu, H Li, Z Cao - Scientific Reports, 2024 - nature.com
Accurate and timely genetic material replication is essential for preserving genomic integrity.
The replication process begins with chromatin licensing and DNA replication factor 1 …

CDT1 drives replication overlicensing and enhances tumorigenesis in the gut

G Monteleone, C Stolfi - The Journal of Pathology, 2023 - Wiley Online Library
Colorectal carcinoma (CRC) is one of the most common forms of malignancy in the Western
world. Recent decades have witnessed enormous progress in our understanding of the …

CUL4A Ubiquitin Ligase Is an Independent Predictor of Overall Survival in Pancreatic Adenocarcinoma

P Tavlas, S Nikou, C Geramoutsou… - Cancer Genomics & …, 2024 - cgp.iiarjournals.org
Abstract Background/Aim: Pancreatic ductal adenocarcinoma (PDAC) is an aggressive
malignancy with dismal prognosis. Genomic instability due to defects in cell-cycle …

Chromatin Licensing and DNA Replication Factor 1 (CDT1) Is a Potential Prognostic Biomarker Involved in the Malignant Biological Behavior of Glioma

T Chen, J Meng, K Yu, T Huang… - ACS Pharmacology & …, 2024 - ACS Publications
Glioma is the primary malignant tumor with the highest incidence rate in the adult central
nervous system. The application of bioinformatics methods to analyze the RNA sequences …

[HTML][HTML] Gd-EOB-DTPA 增强核磁与CDT1 蛋白在肝细胞癌诊疗中的研究进展

赵亚龙, 温生宝 - Advances in Clinical Medicine, 2023 - hanspub.org
肝细胞癌(hepatocellular carcinoma, HCC) 具有高发病率及死亡率, 预后差的临床特点.
为控制不良的临床结果及改善早期诊断和治疗方法, 我们必须在细胞水平上加深对肝细胞癌的 …

Single-Cell Sequencing Analysis and Multiple Machine Learning Methods identified CDT1 as an oncogene in retinoblastoma

Y Yang, Y Zhang, W Xiong, X Yin - 2024 - researchsquare.com
METHODS The scRNA-seq data from RB samples and normal samples obtained from
GSE159977 were analyzed to distinguish cone cells from malignant cone cells using …