Obesity is a major risk factor for the development of insulin resistance and type 2 diabetes.
The exact mechanism by which adipose tissue induces insulin resistance is still unclear. It …

The classical perception of adipose tissue as a storage place of fatty acids has been
replaced over the last years by the notion that adipose tissue has a central role in lipid and …

In the placebo group of the MORE study, including 2576 postmenopausal women (mean
age, 66.5 years), the authors describe a strong linear association between the severity …

Background—Body fat distribution has been cross-sectionally associated with
atherosclerotic disease risk factors, but the prospective relation with coronary heart disease …

There are likely many scenarios and pathways that can lead to metabolic syndrome. This
paper reviews mechanisms by which the accumulation of visceral adipose tissue (VAT) may …

Objective To examine associations between thigh circumference and incident
cardiovascular disease and coronary heart disease and total mortality. Design Prospective …

Background—Upward trends of obesity urge more effective identification of those at
cardiovascular risk. A simple dichotomous indicator, enlarged waist (≥ 88 cm) combined …

A vast number of epidemiological studies suggest an important, but still controversial, role
for obesity and adipose tissue mass in breast cancer risk and an association with tumor …

Females live longer than males, and the estrogens are one of the reasons for this difference.
We reported some years ago that estrogens are able to protect rats against oxidative stress …

OBJECTIVE—To investigate the efficacy of orlistat on the maintenance of weight loss over 3
years following a major weight loss induced by very-low-energy diet (VLED) in obese …