Passage and the evolution of virulence in invertebrate pathogens: Fundamental and applied perspectives

B Raymond, Z Erdos - Journal of Invertebrate Pathology, 2022 - Elsevier
Understanding the ecological and genetic factors that determine the evolution of virulence
has broad value for invertebrate pathology. In addition to helping us understand the …

Metabolic efficiency reshapes the seminal relationship between pathogen growth rate and virulence

RJ Lindsay, PJ Holder, NJ Talbot, I Gudelj - Ecology Letters, 2023 - Wiley Online Library
A cornerstone of classical virulence evolution theories is the assumption that pathogen
growth rate is positively correlated with virulence, the amount of damage pathogens inflict on …

A shift in the virulence potential of Corynebacterium pseudotuberculosis biovar ovis after passage in a murine host demonstrated through comparative proteomics

WM Silva, FA Dorella, SC Soares, GHMF Souza… - BMC microbiology, 2017 - Springer
Background Corynebacterium pseudotuberculosis biovar ovis, a facultative intracellular
pathogen, is the etiologic agent of caseous lymphadenitis in small ruminants. During the …

The global transcription factor Lrp controls virulence modulation in Xenorhabdus nematophila

EA Hussa, ÁM Casanova-Torres… - Journal of …, 2015 - Am Soc Microbiol
The bacterium Xenorhabdus nematophila engages in phenotypic variation with respect to
pathogenicity against insect larvae, yielding both virulent and attenuated subpopulations of …

Quorum sensing sets the stage for the establishment and vertical transmission of Sodalis praecaptivus in tsetse flies

M Medina Munoz, N Spencer, S Enomoto, C Dale… - PLoS …, 2020 - journals.plos.org
Bacterial virulence factors facilitate host colonization and set the stage for the evolution of
parasitic and mutualistic interactions. The Sodalis-allied clade of bacteria exhibit striking …

Trade-offs shape the evolution of the vector-borne insect pathogen Xenorhabdus nematophila

E Chapuis, A Arnal, JB Ferdy - Proceedings of the …, 2012 - royalsocietypublishing.org
Our current understanding on how pathogens evolve relies on the hypothesis that
pathogens' transmission is traded off against host exploitation. In this study, we surveyed the …

Nematode–bacteria mutualism: Selection within the mutualism supersedes selection outside of the mutualism

LT Morran, MKJ Penley, VS Byrd, AJ Meyer… - …, 2016 - academic.oup.com
The coevolution of interacting species can lead to codependent mutualists. Little is known
about the effect of selection on partners within verses apart from the association. Here, we …

Method for serial passage of infectious hematopoietic necrosis virus (IHNV) in rainbow trout

J Doumayrou, MG Ryan, AR Wargo - Diseases of aquatic organisms, 2019 - int-res.com
Transmission is a fundamental component of pathogen fitness. A better understanding of
pathogen transmission can greatly improve disease management. In particular, controlled …

Quantitative Proteomic Analysis Reveals Changes in the Benchmark Corynebacterium pseudotuberculosis Biovar Equi Exoproteome after Passage in a Murine Host

WM Silva, RDDO Carvalho, FA Dorella… - Frontiers in Cellular …, 2017 - frontiersin.org
Corynebacterium pseudotuberculosis biovar equi is the etiologic agent of ulcerative
lymphangitis. To investigate proteins that could be related to the virulence of this pathogen …

Mechanisms involved in the adaptation of Escherichia coli O157:H7 to the host intestinal microenvironment

RJ Fernandez-Brando, SP McAteer… - Clinical …, 2020 - portlandpress.com
Host adaptation of pathogens may increase intra-and interspecies transmission. We showed
previously that the passage of a clinically isolated enterohemorrhagic Escherichia coli …