The state of complement in COVID-19
Hyperactivation of the complement and coagulation systems is recognized as part of the
clinical syndrome of COVID-19. Here we review systemic complement activation and local …
clinical syndrome of COVID-19. Here we review systemic complement activation and local …
Thromboembolism risk of COVID-19 is high and associated with a higher risk of mortality: a systematic review and meta-analysis
Background Studies have suggested that there is increased risk of thromboembolism (TE)
associated with coronavirus disease 2019 (COVID-19). However, overall arterial and …
associated with coronavirus disease 2019 (COVID-19). However, overall arterial and …
2022 ACC expert consensus decision pathway on cardiovascular sequelae of COVID-19 in adults: myocarditis and other myocardial involvement, post-acute …
Writing Committee, TJ Gluckman, NM Bhave… - Journal of the American …, 2022 - jacc.org
The American College of Cardiology (ACC) has a long history of developing documents (eg,
decision pathways, health policy statements, appropriate use criteria) to provide members …
decision pathways, health policy statements, appropriate use criteria) to provide members …
Efficacy and safety of therapeutic-dose heparin vs standard prophylactic or intermediate-dose heparins for thromboprophylaxis in high-risk hospitalized patients with …
AC Spyropoulos, M Goldin, D Giannis… - JAMA internal …, 2021 - jamanetwork.com
Importance Hospitalized patients with COVID-19 are at risk for venous and arterial
thromboembolism and death. Optimal thromboprophylaxis dosing in high-risk patients is …
thromboembolism and death. Optimal thromboprophylaxis dosing in high-risk patients is …
[HTML][HTML] Emerging variants of SARS-CoV-2 and novel therapeutics against coronavirus (COVID-19)
A Aleem, AS Ab, AK Slenker - 2021 - europepmc.org
Objectives: Describe the clinical manifestations, including extrapulmonary manifestations of
COVID-19. Outline the latest treatments available in the management of COVID-19 …
COVID-19. Outline the latest treatments available in the management of COVID-19 …
Neurologic involvement in children and adolescents hospitalized in the United States for COVID-19 or multisystem inflammatory syndrome
KL LaRovere, BJ Riggs, TY Poussaint… - JAMA …, 2021 - jamanetwork.com
Importance Coronavirus disease 2019 (COVID-19) affects the nervous system in adult
patients. The spectrum of neurologic involvement in children and adolescents is unclear …
patients. The spectrum of neurologic involvement in children and adolescents is unclear …
Pulmonary embolism and deep vein thrombosis in COVID-19: a systematic review and meta-analysis
Background The association of pulmonary embolism (PE) with deep vein thrombosis (DVT)
in patients with coronavirus disease 2019 (COVID-19) remains unclear, and the diagnostic …
in patients with coronavirus disease 2019 (COVID-19) remains unclear, and the diagnostic …
COVID-19-associated coagulopathy and disseminated intravascular coagulation
The pathology of coronavirus disease 2019 (COVID-19) is exacerbated by the progression
of thrombosis, and disseminated intravascular coagulation (DIC), and cytokine storms. The …
of thrombosis, and disseminated intravascular coagulation (DIC), and cytokine storms. The …
Loss of Bcl-6-expressing T follicular helper cells and germinal centers in COVID-19
Humoral responses in coronavirus disease 2019 (COVID-19) are often of limited durability,
as seen with other human coronavirus epidemics. To address the underlying etiology, we …
as seen with other human coronavirus epidemics. To address the underlying etiology, we …
[HTML][HTML] Viral presence and immunopathology in patients with lethal COVID-19: a prospective autopsy cohort study
B Schurink, E Roos, T Radonic, E Barbe… - The Lancet …, 2020 - thelancet.com
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) targets
multiple organs and causes severe coagulopathy. Histopathological organ changes might …
multiple organs and causes severe coagulopathy. Histopathological organ changes might …