Promotion of IL‑17/NF‑κB signaling in autoimmune thyroid diseases

Y Lu, C Xing, C Zhang, X Lv, G Liu… - Experimental and …, 2022 - spandidos-publications.com
IL-17 and other cytokines have a number of immunomodulatory effects on thyroid cells. The
present study investigated the changes and correlations amongst IL-17, NF-κB, IL-6, IL-10 …

Single-cell transcriptional profiling of clear cell renal cell carcinoma reveals a tumor-associated endothelial tip cell phenotype

J Zvirblyte, J Nainys, S Juzenas, K Goda… - Communications …, 2024 - nature.com
Clear cell renal cell carcinoma (ccRCC) is the most prevalent form of renal cancer,
accounting for over 75% of cases. The asymptomatic nature of the disease contributes to …

inDrops-2: a flexible, versatile and cost-efficient droplet microfluidics approach for high-throughput scRNA-seq of fresh and preserved clinical samples

S Juzenas, V Kiseliovas, K Goda, J Zvirblyte… - bioRxiv, 2023 - biorxiv.org
The development of a large variety of single-cell analytical techniques has empowered
researchers to explore diverse biological questions at the level of individual cells. Among …

Single-cell transcriptional profiling of clear cell renal cell carcinoma reveals an invasive tumor vasculature phenotype

J Zvirblyte, J Nainys, S Juzenas, R Kubiliute, M Kincius… - bioRxiv, 2023 - biorxiv.org
Clear cell renal cell carcinoma (ccRCC) is the most prevalent form of renal cancer,
accounting for over 75% of cases. The asymptomatic nature of the disease contributes to …

ctQC improves biological inferences from single cell and spatial transcriptomics data

V Lakshmanan, M Kahraman, DC Macalinao, N Gunn… - bioRxiv, 2024 - biorxiv.org
Quality control (QC) is the first critical step in single cell and spatial data analysis pipelines.
QC is particularly important when analysing data from primary human samples, since …