ABSTRACT Introduction Soft mist inhalers (SMIs) are propellant-free inhalers that utilize
mechanical power to deliver single or multiple doses of inhalable drug aerosols in the form …

Aquatic eutrophication, often with anthropogenic causes, facilitates blooms of cyanobacteria
including cyanotoxin producing species, which profoundly impact aquatic ecosystems and …

Background Intranasal vaccination may induce protective local and systemic immune
responses against respiratory pathogens. A number of intranasal SARS-CoV-2 vaccine …

A limitation of current SARS-CoV-2 vaccines is that they provide minimal protection against
infection with current Omicron subvariants,, although they still provide protection against …

Increasing global concerns of pandemic respiratory viruses highlight the importance of
developing optimal vaccination strategies that encompass vaccine platform, delivery route …

The world is in need of next-generation COVID-19 vaccines. Although first-generation
injectable COVID-19 vaccines continue to be critical tools in controlling the current global …

Inducing humoral and cytotoxic mucosal immunity at the sites of pathogen entry has the
potential to prevent the infection from getting established. This is different from systemic …

Many of the current pandemic threats are caused by viruses that infect the respiratory tract.
Remarkably though, the majority of vaccines and antiviral drugs are administered via …

Purpose Intratracheal delivery and consistent dosing of dry powder vaccines is especially
challenging in mice. To address this issue, device design of positive pressure dosators and …

SARS-CoV-2 continues to pose a global threat, and current vaccines, while effective against
severe illness, fall short in preventing transmission. To address this challenge, there's a …