Current trends on bioengineering approaches for ovarian microenvironment reconstruction

GHDR Almeida, RP Iglesia, JC Rinaldi… - … Engineering Part B …, 2023 - liebertpub.com
Ovarian tissue has a unique microarchitecture and a complex cellular and molecular
dynamics that are essential for follicular survival and development. Due to this great …

Induction of aryl hydrocarbon receptor in granulosa cells by endoplasmic reticulum stress contributes to pathology of polycystic ovary syndrome

C Kunitomi, M Harada, A Kusamoto… - Molecular Human …, 2021 - academic.oup.com
Recent studies have uncovered the critical role of aryl hydrocarbon receptor (AHR) in
various diseases, including obesity and cancer progression, independent of its previously …

Epigenetic modifications of gonadotropin receptors can regulate follicular development

Y Yang, W Feng, J Zhou, R Zhang, X Lin… - Animal Reproduction …, 2024 - Elsevier
The spatiotemporal transcription of follicle-stimulating hormone receptor (FSHR) and
luteinizing hormone/human chorionic gonadotropin receptor (LHCGR) are crucial events for …

Pathophysiological changes in female rats with estrous cycle disorder induced by long‐term heat stress

GH An, XW Chen, C Li, L Zhang, MF Wei… - BioMed Research …, 2020 - Wiley Online Library
High‐temperature exposure is detrimental to women's reproductive health; however, the
impact caused by long‐term high temperature is not comprehensive, and a stable model of …

High levels of follicular fluid testosterone could impair oocyte developmental competency via affecting aryl hydrocarbon receptor pathway in PCOS patients

F Eini, MA Kutenaei, T Foroutan, E Salehi - BMC Molecular and Cell …, 2022 - Springer
Background Although hormonal and metabolic dysfunction have been recognized as a
possible cause of polycystic ovarian syndrome (PCOS), the associations between …

[HTML][HTML] In vitro exposure to triazoles used as fungicides impairs human granulosa cells steroidogenesis

L Serra, A Estienne, G Caria, C Ramé, C Jolivet… - Environmental …, 2023 - Elsevier
Triazoles are the main components of fungicides used in conventional agriculture. Some
data suggests that they may be endocrine disruptors. Here, we found five triazoles …

[HTML][HTML] Triazole pesticides exposure impaired steroidogenesis associated to an increase in AHR and CAR expression in testis and altered sperm parameters in …

L Serra, G Bourdon, A Estienne, M Fréville, C Ramé… - Toxicology Reports, 2023 - Elsevier
Since several decades, we observe the decline of various bird populations that could be
partly linked to the agricultural intensification and the use of large amount of pesticides …

Bisphenol analogs AF, S and F: Effects on functional characteristics of porcine granulosa cells

AB Mlynarcikova, S Scsukova - Reproductive Toxicology, 2021 - Elsevier
In order to replace industrial functions of the restricted endocrine disruptor bisphenol A
(BPA), its structural analogs are increasingly employed without adequate assessment of …

Assisted reproductive technology and interactions between serum basal FSH/LH and ovarian sensitivity index

Y He, L Liu, F Yao, C Sun, M Meng, Y Lan… - Frontiers in …, 2023 - frontiersin.org
Objectives This study aimed to investigate whether the FSH (follicle-stimulating
hormone)/LH (Luteinizing hormone) ratio correlates with ovarian response in a cross …

[HTML][HTML] Advancing 3Rs: The Mouse Estrus Detector (MED) as a Low-Stress, Painless, and Efficient Tool for Estrus Determination in Mice

IV Belozertseva, DD Merkulovs, H Kaiser… - International Journal of …, 2024 - mdpi.com
Determining the estrous cycle stages in mice is essential for optimizing breeding strategies,
synchronizing experimental timelines, and facilitating studies in behavior, drug testing, and …