Aging is characterized by systemic chronic inflammation, which is accompanied by cellular
senescence, immunosenescence, organ dysfunction, and age-related diseases. Given the …

Aging is a gradual and irreversible pathophysiological process. It presents with declines in
tissue and cell functions and significant increases in the risks of various aging-related …

Ageing organisms accumulate senescent cells that are thought to contribute to body
dysfunction. Telomere shortening and damage are recognized causes of cellular …

Bone is a dynamic organ maintained by tightly regulated mechanisms. With old age, bone
homeostasis, which is maintained by an intricate balance between bone formation and bone …

The New York Times bestselling book coauthored by the Nobel Prize winner who
discovered telomerase and telomeres' role in the aging process and the health psychologist …

With the global increase of the elderly population, the improvement of the treatment for
various aging-related diseases and the extension of a healthy lifespan have become some …

Bone marrow derived mesenchymal progenitor cells (MPCs) play an important role in bone
homeostasis. Age-related changes occur in bone resulting in a decrease in bone density …

The interest in bone marrow adiposity (BMA) has increased over the last decade due to its
association with, and potential role, in a range of diseases (osteoporosis, diabetes …

Osteoporosis is characterized by low bone mass and an increased risk of fracture. Genetic
factors, environmental factors and gene–environment interactions all contribute to a person's …

Progeroid mouse models display phenotypes in multiple organ systems that suggest
premature aging and resemble features of natural aging of both mice and humans. The …