Antiangiogenic cancer treatment: The great discovery and greater complexity

E Maj, D Papiernik, J Wietrzyk - … journal of oncology, 2016 - spandidos-publications.com
The discovery of tumor angiogenesis opened a new path in fighting cancer. The approval of
different antiangiogenic agents, most targeting vascular endothelial growth factor (VEGF) …

Vitamin D in cancer chemoprevention

M Giammanco, D Di Majo, M La Guardia… - Pharmaceutical …, 2015 - Taylor & Francis
Context: There is increasing evidence that Vitamin D (Vit D) and its metabolites, besides
their well-known calcium-related functions, may also exert antiproliferative, pro …

Vitamin D alleviates lead induced renal and testicular injuries by immunomodulatory and antioxidant mechanisms in rats

MA BaSalamah, AH Abdelghany, M El-Boshy… - Scientific reports, 2018 - nature.com
This study measured the effects of vitamin D (VD) supplementation on the underlying
molecular pathways involved in renal and testicular damage induced by lead (Pb) toxicity …

The roles of UVB and vitamin D in reducing risk of cancer incidence and mortality: A review of the epidemiology, clinical trials, and mechanisms

M Moukayed, WB Grant - Reviews in Endocrine and Metabolic Disorders, 2017 - Springer
Global cancer incidence and mortality rates are high and increasing. Thus, it is imperative to
find novel solutions to preventing cancer incidence and treating it at an affordable yet …

[HTML][HTML] Calcipotriol, a synthetic Vitamin D analog, promotes antitumor immunity via CD4+ T-dependent CTL/NK cell activation

H Kim, J Kim, JK Sa, BK Ryu, KJ Park, J Kim… - Biomedicine & …, 2022 - Elsevier
To overcome the hurdles of immunotherapy, we investigated whether calcipotriol, a synthetic
vitamin D analog, could overcome the immune evasion of glioblastoma multiforme (GBM) by …

[PDF][PDF] The renaissance of vitamin D

J Wierzbicka, A Piotrowska… - Acta Biochimica …, 2014 - bibliotekanauki.pl
There is no doubt that vitamin D plays a crucial role in the maintenance of musculoskeletal
system. But the function of this ancient molecule presumably ranges far beyond hormone …

Vitamin D3 enhances the tumouricidal effects of 5-Fluorouracil through multipathway mechanisms in azoxymethane rat model of colon cancer

B Refaat, AG El-Shemi, OA Kensara… - Journal of Experimental …, 2015 - Springer
Background Vitamin D3 and its analogues have recently been shown to enhance the anti-
tumour effects of 5-Fluorouracil (5-FU) both in vitro and in xenograft mouse model of colon …

Vitamin D: Skin, sunshine, and beyond

E Alia, PE Kerr - Clinics in dermatology, 2021 - Elsevier
AbstractEdited by E. Alia, PE Kerr delete this edited stuff. I don't know from where this is
originating Vitamin D is a steroid hormone of importance to the field of dermatology. Skin is …

Circulating vitamin D level and its impact on mortality and recurrence in stage III colorectal cancer patients: a systematic review and meta-analysis

A Ottaiano, S Facchini, M Santorsola, G Nasti… - Cancers, 2023 - mdpi.com
Simple Summary We conducted a systematic review and meta-analysis to investigate the
relationship between pre-operative vitamin D (VD) levels and time-to-outcome in stage III …

Calcitriol and its analogs establish the immunosuppressive microenvironment that drives metastasis in 4T1 mouse mammary gland cancer

A Pawlik, A Anisiewicz, B Filip-Psurska… - International Journal of …, 2018 - mdpi.com
In our previous study, calcitriol and its analogs PRI-2191 and PRI-2205 stimulated 4T1
mouse mammary gland cancer metastasis. Therefore, we aimed to analyze the inflammatory …