Microorganisms engage in complex interactions with other members of the microbial
community, higher organisms as well as their environment. However, determining the exact …

Highlights•Anaerobic microbes play a significant role in the global biogeochemical
cycle.•Mathematical models explain anaerobic processes, including bioconversion abilities …

RAVEN is a commonly used MATLAB toolbox for genome-scale metabolic model (GEM)
reconstruction, curation and constraint-based modelling and simulation. Here we present …

The accumulation of volatile fatty acids (VFAs) caused by antibiotic inhibition significantly
reduces the treatment efficiency of sulfamethoxazole (SMX) wastewater. Few studies have …

The accumulation of volatile fatty acids, particularly propionic acid, significantly inhibits the
efficiency of the anaerobic digestion system. In propionate degradation metabolism, the …

Advances in high-throughput sequencing technologies and bioinformatics approaches over
almost the last three decades have substantially increased our ability to explore …

Microbial communities are pervasive in the natural environment, associated with many
hosts, and of increasing importance in biotechnological applications. The complexity of …

Abstract “In silico organisms” are computational genome-scale metabolic models used in
systems and synthetic biology developed by constraint-based metabolic simulations using …

In nature, microbes do not exist in isolation but co-exist in a variety of ecological and
biological environments and on various host organisms. Due to their close proximity, these …

Constraint-based modeling (CBM) is increasingly used to analyze the metabolism of
complex microbial communities involved in ecology, biomedicine, and various …