Toxic megacolon (TM) is an infrequent but devastating complication of colitis. Numerous
forms of colonic inflammation can give rise to TM but the majority occur in individuals with …

Neurohumoral substances and their receptors play a major part in the complex regulation of
gastrointestinal motility and have therefore been the predominant targets for drug …

Clinical investigations in inflammatory bowel disease (IBD) patients have provided
increasing evidence that eosinophils contribute to chronic intestinal inflammation …

Impaired colon motility is one of the leading problems associated with inflammatory bowel
disease (IBD). An expanding body of evidence supports the role of microbiome in normal gut …

Neurogenic mechanisms have been implicated in the induction of inflammatory bowel
disease (IBD). Vanilloid receptor type 1 (TRPV1) has been visualized on nerve terminals of …

Inflammation and immune activation in the gut are usually accompanied by alteration of
gastrointestinal (GI) motility. In infection, changes in motor function have been linked to host …

The relationship between motility and inflammatory gastrointestinal disorders is at the same
time complex and intriguing since these conditions might share some genetic …

Abdominal pain is a common symptom in patients with inflammatory bowel disease (IBD)
that negatively affects quality of life and can lead to increased health-seeking behavior …

Feeding intolerance and the development of ileus is a common complication affecting
critically ill, surgical, and trauma patients, resulting in prolonged intensive care unit and …

Intestinal inflammation alters the contractile activity of intestinal smooth muscle. Motility
disorders of the gastrointestinal tract are clinically important symptoms, because they are …