Among the family of phospholipases A 2 (PLA 2 s) are the Ca 2+-independent PLA 2 s (iPLA
2 s) and they are designated group VI iPLA 2 s. In relation to secretory and cytosolic PLA 2 s …

Capacitation is a series of morphological and metabolic changes necessary for the
spermatozoon to achieve fertilizing ability. One of the earlier happenings during mammalian …

Artificial enzymes have attracted wide interest in disease diagnosis and biotechnology due
to high stability, easy synthesis, and cost effectiveness. Unfortunately, their catalytic rate is …

Peroxiredoxin 6 (Prdx6, 1-cys peroxiredoxin) is a unique member of the peroxiredoxin family
that, in contrast to other mammalian peroxiredoxins, lacks a resolving cysteine and uses …

For cytosine (C) demethylation of vertebrate DNA, it is known that the TET proteins could
convert 5-methyl C (5-mC) to 5-hydroxymethyl C (5-hmC). However, DNA …

Peroxiredoxin 6 (Prdx6) is a Ca 2+-independent intracellular phospholipase A 2 (called
aiPLA 2) that is localized to cytosol, lysosomes, and lysosomal-related organelles. Activity is …

Abstract Peroxiredoxin 6 (PRDX6) has been associated with tumor progression and cancer
metastasis. Its acting on phospholipid hydroperoxides and its phospholipase-A2 activity are …

Introduction Circulating extracellular histones acquire relevance as cytotoxic mediators in
sepsis. Extracellular histones act as damage-associated molecular patterns (DAMPs), which …

Peroxiredoxin 6 (Prdx6) is a member of an evolutionary ancient family of peroxidase
enzymes with diverse functions in the cell. Prdx6 is an important enzymatic antioxidant. It …

Drug resistance and virulence of Mycobacterium tuberculosis are partially related to the
pathogen's antioxidant systems. Peroxide detoxification in this bacterium is achieved by the …