Antimicrobial peptides: an update on classifications and databases

A Bin Hafeez, X Jiang, PJ Bergen, Y Zhu - International journal of …, 2021 - mdpi.com
Antimicrobial peptides (AMPs) are distributed across all kingdoms of life and are an
indispensable component of host defenses. They consist of predominantly short cationic …

[HTML][HTML] Mechanism of the binding, insertion and destabilization of phospholipid bilayer membranes by α-helical antimicrobial and cell non-selective membrane-lytic …

Y Shai - Biochimica et Biophysica Acta (BBA)-Biomembranes, 1999 - Elsevier
Permeation of the cell membrane leading to cell death is a mechanism used by a large
number of membrane-lytic peptides. Some are linear, mostly helical, and others contain one …

Mode of action of membrane active antimicrobial peptides

Y Shai - Peptide Science: Original Research on Biomolecules, 2002 - Wiley Online Library
Water‐membrane soluble protein and peptide toxins are used in the defense and offense
systems of all organisms, including plants and humans. A major group includes …

Theory, practice, and applications of paramagnetic relaxation enhancement for the characterization of transient low-population states of biological macromolecules …

GM Clore, J Iwahara - Chemical reviews, 2009 - ACS Publications
Understanding the function of biological macromolecules and their complexes at the
physicochemical level requires knowledge of both their structure and dynamics …

Visualizing transient dark states by NMR spectroscopy

NJ Anthis, GM Clore - Quarterly Reviews of Biophysics, 2015 - cambridge.org
Myriad biological processes proceed through states that defy characterization by
conventional atomic-resolution structural biological methods. The invisibility of these …

From “carpet” mechanism to de-novo designed diastereomeric cell-selective antimicrobial peptides

Y Shai, Z Oren - Peptides, 2001 - Elsevier
Living organisms of all types produce a large repertoire of gene-encoded, net positively
charged, antimicrobial peptides as part of their innate immunity to microbial invasion …

Peptaibols: models for ion channels

JK Chugh, BA Wallace - Biochemical Society Transactions, 2001 - portlandpress.com
Peptaibols are membrane-active polypeptides isolated from fungal sources. They are
characterized by the presence of an unusual amino acid, α-aminoisobutyric acid, and a C …

Exploring peptide membrane interaction using surface plasmon resonance: differentiation between pore formation versus membrane disruption by lytic peptides

N Papo, Y Shai - Biochemistry, 2003 - ACS Publications
Lytic peptides comprise a large group of membrane-active peptides used in the defensive
and offensive systems of all organisms. Differentiating between their modes of interaction …

Lipopeptaibols, a novel family of membrane active, antimicrobial peptides

C Toniolo, M Crisma, F Formaggio, C Peggion… - Cellular and Molecular …, 2001 - Springer
Lipopeptaibols are members of a novel group of naturally occurring, short peptides with
antimicrobial activity, characterized by a lipophilic acyl chain at the N-terminus, a high …

[HTML][HTML] Effects of the antimicrobial peptide PGLa on live Escherichia coli

A da Silva Jr, O Teschke - Biochimica et Biophysica Acta (BBA)-Molecular …, 2003 - Elsevier
The activity of PGLa, an antimicrobial peptide isolated from hemocytes of frog skin and its
secretions on living Escherichia coli, was investigated by imaging the cells with atomic force …