Harnessing endogenous stimuli for responsive materials in theranostics
Materials that respond to endogenous stimuli are being leveraged to enhance
spatiotemporal control in a range of biomedical applications from drug delivery to diagnostic …
spatiotemporal control in a range of biomedical applications from drug delivery to diagnostic …
[HTML][HTML] Pharmacokinetic aspects of retinal drug delivery
Drug delivery to the posterior eye segment is an important challenge in ophthalmology,
because many diseases affect the retina and choroid leading to impaired vision or …
because many diseases affect the retina and choroid leading to impaired vision or …
Recent advances of controlled drug delivery using microfluidic platforms
Conventional systematically-administered drugs distribute evenly throughout the body, get
degraded and excreted rapidly while crossing many biological barriers, leaving minimum …
degraded and excreted rapidly while crossing many biological barriers, leaving minimum …
Hydrogel biomaterials for application in ocular drug delivery
CR Lynch, PPD Kondiah, YE Choonara… - … in bioengineering and …, 2020 - frontiersin.org
There are many challenges involved in ocular drug delivery. These are a result of the many
tissue barriers and defense mechanisms that are present with the eye; such as the cornea …
tissue barriers and defense mechanisms that are present with the eye; such as the cornea …
Cellulosic polymers for enhancing drug bioavailability in ocular drug delivery systems
One of the major impediments to drug development is low aqueous solubility and thus poor
bioavailability, which leads to insufficient clinical utility. Around 70–80% of drugs in the …
bioavailability, which leads to insufficient clinical utility. Around 70–80% of drugs in the …
[HTML][HTML] Intravitreal hydrogels for sustained release of therapeutic proteins
BC Ilochonwu, A Urtti, WE Hennink… - Journal of Controlled …, 2020 - Elsevier
This review highlights how hydrogel formulations can improve intravitreal protein delivery to
the posterior segment of the eye in order to increase therapeutic outcome and patient …
the posterior segment of the eye in order to increase therapeutic outcome and patient …
Advanced implantable drug delivery technologies: transforming the clinical landscape of therapeutics for chronic diseases
FP Pons-Faudoa, A Ballerini, J Sakamoto… - Biomedical …, 2019 - Springer
Chronic diseases account for the majority of all deaths worldwide, and their prevalence is
expected to escalate in the next 10 years. Because chronic disorders require long-term …
expected to escalate in the next 10 years. Because chronic disorders require long-term …
Electrochemical and Electrical Biosensors for Wearable and Implantable Electronics Based on Conducting Polymers and Carbon-Based Materials
Bioelectronic devices are designed to translate biological information into electrical signals
and vice versa, thereby bridging the gap between the living biological world and electronic …
and vice versa, thereby bridging the gap between the living biological world and electronic …
Hydrogel-based ocular drug delivery systems: Emerging fabrication strategies, applications, and bench-to-bedside manufacturing considerations
RC Cooper, H Yang - Journal of controlled release, 2019 - Elsevier
The physiological barriers of the eye pose challenges to the delivery of the array of
therapeutics for ocular diseases. Hydrogels have been widely explored for medical …
therapeutics for ocular diseases. Hydrogels have been widely explored for medical …
Additive manufacturing in drug delivery: Innovative drug product design and opportunities for industrial application
H Ragelle, S Rahimian, EA Guzzi… - Advanced Drug Delivery …, 2021 - Elsevier
Additive manufacturing (AM) or 3D printing is enabling new directions in product design. The
adoption of AM in various industrial sectors has led to major transformations. Similarly, AM …
adoption of AM in various industrial sectors has led to major transformations. Similarly, AM …