Clinical biology of the pituitary adenoma

S Melmed, UB Kaiser, MB Lopes, J Bertherat… - Endocrine …, 2022 - academic.oup.com
All endocrine glands are susceptible to neoplastic growth, yet the health consequences of
these neoplasms differ between endocrine tissues. Pituitary neoplasms are highly prevalent …

A Pituitary Society update to acromegaly management guidelines

M Fleseriu, BMK Biller, PU Freda, MR Gadelha… - Pituitary, 2021 - Springer
Guidelines and consensus statements ensure that physicians managing acromegaly
patients have access to current information on evidence-based treatments to optimize …

Systemic complications of acromegaly and the impact of the current treatment landscape: an update

MR Gadelha, L Kasuki, DST Lim… - Endocrine reviews, 2019 - academic.oup.com
Acromegaly is a chronic systemic disease with many complications and is associated with
increased mortality when not adequately treated. Substantial advances in acromegaly …

Acromegaly: an endocrine society clinical practice guideline

L Katznelson, ER Laws Jr, S Melmed… - The Journal of …, 2014 - academic.oup.com
Objective: The aim was to formulate clinical practice guidelines for acromegaly. Participants:
The Task Force included a chair selected by the Endocrine Society Clinical Guidelines …

Pasireotide versus octreotide in acromegaly: a head-to-head superiority study

A Colao, MD Bronstein, P Freda, F Gu… - The Journal of …, 2014 - academic.oup.com
Context: Biochemical control reduces morbidity and increases life expectancy in patients
with acromegaly. With current medical therapies, including the gold standard octreotide long …

Complications of acromegaly: cardiovascular, respiratory and metabolic comorbidities

R Pivonello, RS Auriemma, LFS Grasso, C Pivonello… - Pituitary, 2017 - Springer
Acromegaly is associated with an enhanced mortality, with cardiovascular and respiratory
complications representing not only the most frequent comorbidities but also two of the main …

Acromegaly incidence, prevalence, complications and long-term prognosis: a nationwide cohort study

J Dal, U Feldt-Rasmussen, M Andersen… - European Journal of …, 2016 - academic.oup.com
Abstract Design Valid data on acromegaly incidence, complications and mortality are
scarce. The Danish Health Care System enables nationwide studies with complete follow-up …

Mortality in acromegaly decreased in the last decade: a systematic review and meta-analysis

F Bolfi, AF Neves, CL Boguszewski… - European Journal of …, 2018 - academic.oup.com
Objective To compare the acromegaly mortality rates with those expected for the general
population from studies published before and after 2008. Methods We performed a …

Successful mortality reduction and control of comorbidities in patients with acromegaly followed at a highly specialized multidisciplinary clinic

M Mercado, B Gonzalez, G Vargas… - The Journal of …, 2014 - academic.oup.com
Context: Acromegaly is usually due to the excessive secretion of GH by a pituitary adenoma.
It is frequently accompanied by comorbidities that compromise quality of life and results in …

[PDF][PDF] Mortality in acromegaly: a 20-year follow-up study

E Ritvonen, E Löyttyniemi, P Jaatinen, T Ebeling… - Endocr Relat …, 2016 - academia.edu
Objective: It is unclear whether mortality still is increased in acromegaly and whether there
are gender-related differences. We dynamically assessed outcome during long-term follow …